GENERAL PURPOSE BRAIN-COMPUTER INTERFACE(BCI)SYSTEM

通用脑机接口（BCI）系统

基本信息

批准号：
6788863
负责人：
Jonathan Rickel Wolpaw
金额：
$ 67.82万
依托单位：
WADSWORTH CENTER
依托单位国家：
美国
项目类别：
财政年份：
2002
资助国家：
美国
起止时间：
2002-09-20 至 2007-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/6788863
关键词：
bioengineering /biomedical engineering biological information processing biomedical equipment development brain electrical activity clinical research communication disorder aid computer human interaction computer program /software human subject nervous system prosthesis neuromuscular disorder patient oriented research

项目摘要

DESCRIPTION (provided by applicant): Signals from the brain can provide a new communication channel - a brain-computer interface (BCI) - for those with severe neuromuscular disorders such as amyotrophic lateral sclerosis, brainstem stroke, and spinal cord injury. BCI technology can allow people who are completely paralyzed, or "locked in," to express wishes to caregivers, use word processing programs, access the Internet, or even operate neuroprostheses. Up to now, BCI research has demonstrated that a variety of different methods using different brain signals, signal analyses, and operating formats can convey a persons commands to a computer. Future progress that moves from this demonstration stage to practical applications of long-term value to those with motor disabilities requires a flexible general purpose BCI system that can incorporate, compare, and (if indicated) combine these different methods, and can support generation of standard protocols for the clinical application of this new communication and control technology. The development and clinical validation of a general purpose BCI system is the goal of this Bioengineering Research Partnership (BRP) application. Each of the investigators in this partnership has been in the forefront of research into one of the current BCI methods, and together they have extensive experience in the development of BCI systems. The aims of this proposal are: (1) to develop a flexible general purpose BCI system that can incorporate any of the relevant signals, analyses, and operating formats and can be configured for laboratory or clinical needs; (2) to use the system to compare, contrast, and combine relevant brain signals and signal processing options during BCI operation and thereby develop a standard protocol for applying BCI technology to the needs of individual users; (3) to apply the system and protocol to address specific communication needs of people with severe motor disabilities and show that BCI technology is both useful to and actually used by these individuals;(4) to apply the system and protocol to develop the use of neuronal activity recorded within cortex for communication and control, and to define the relationships between this intracortical activity and scalp-recorded signals that might be used to guide or supplement invasive methods. Achievement of these aims and dissemination of the resulting technology to other research groups should advance BCI research from its current stage of laboratory demonstrations to development and validation of a general purpose BCI communication and control technology that can incorporate all relevant brain signals and has clear practical value for those with motor disabilities.

描述（由申请人提供）：来自大脑的信号可以提供新的通信通道 - 脑部计算机界面（BCI） - 对于患有严重神经肌肉疾病的人，例如肌萎缩性侧向硬化症，脑干中风和脊髓损伤。 BCI技术可以允许那些完全瘫痪或“锁定”的人向看护人，使用文字处理程序，访问互联网甚至操作神经propthess。到目前为止，BCI研究表明，使用不同的大脑信号，信号分析和操作格式的多种不同方法可以将人命令传达给计算机。从这个演示阶段转变为长期价值对运动障碍者的实际应用的未来进步需要灵活的通用BCI系统，该系统可以合并，比较和（如果指示）结合这些不同的方法，并可以支持标准的生成该新通信和控制技术的临床应用方案。通用BCI系统的开发和临床验证是该生物工程研究伙伴关系（BRP）应用程序的目标。该合作伙伴关系中的每个研究人员都处于研究当前BCI方法之一的研究的最前沿，并且在BCI系统的开发中，他们共同拥有丰富的经验。该提案的目的是：（1）开发灵活的通用BCI系统，该系统可以包含任何相关的信号，分析和操作格式，并可以根据实验室或临床需求进行配置；（2）使用系统在BCI操作过程中比较，对比和结合相关的大脑信号和信号处理选项，从而为将BCI技术应用于个人用户的需求开发标准协议；（3）应用系统和协议来满足严重运动残障人士的特定通信需求，并表明BCI技术既适用又对这些人实际使用；（4）应用系统和协议来开发使用的使用在皮质中记录的神经元活动以进行通信和控制，并定义了这种物质内活动与可能用于指导或补充侵入性方法的头皮录制信号之间的关系。实现这些目标并将最终技术传播给其他研究小组应将BCI研究从当前的实验室演示阶段提高到通用BCI通信和控制技术的开发和验证，该技术可以纳入所有相关的大脑信号，并具有明确的实践价值对于那些有运动障碍的人。