P-30 Core Grant for Vision Research

P-30 视觉研究核心补助金

• 批准号: 6718980
• 负责人: Vadim Y Arshavsky
• 金额: $ 56.08万
• 依托单位: MASSACHUSETTS EYE AND EAR INFIRMARY
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-04-01 至 2007-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6718980
• 关键词: biomedical facility; vision

This is a new application from vision scientists at the Massachusetts Eye and Ear Infirmary seeking support for shared facilities and services. We aim to enhance the productivity of our individual research programs, create opportunities for new research endeavors, and promote collaborative efforts in identifying the molecular, cellular and genetic bases of normal eye function and the origins of eye diseases. Support is requested for four modules. 1. The Morphology and Microscopy Module will provide resources, services and technical assistance in conducting laser scanning confocal microscopy, transmission electron microscopy, and light microscopy. 2. The Molecular Biology Module will provide DNA sequencing and general molecular biology services and supplies. In addition, it will support the maintenance of shared equipment and the management and operation of the imaging center and the tissue culture facility. 3. The Computer Service Module will provide researchers with technical assistance to optimize computer configurations for research purposes, interface computers with laboratory equipment, create and maintain databases, transfer and store large data and image files, and maintain a server dedicated for use by the research community. It will also provide extensive support for the other modules of this Core Grant. 4. The Clinical Interface Module will provide assistance to research programs requiring human blood collection. It will facilitate the preparation and storage of lymphocyte pellets, preparation of DNA samples, and maintenance of databases containing clinical information related to patients with stored blood samples. Our Department is committed to the philosophy that the most efficient research program should be built on a multi-disciplinary approach involving the efforts of both basic and clinical scientists. Following a tradition of strong institutional support, the Department maintains a superb environment for the research endeavors discussed in this application. This core grant will provide important resources to guarantee the continued excellence of our program and will contribute critical resources for further teaching and research opportunities.

这是马萨诸塞州眼和耳科医院的远见科学家的新应用，寻求对共享设施和服务的支持。我们旨在提高个人研究计划的生产力，为新研究创造机会，并促进合作努力，以确定正常眼功能的分子，细胞和遗传基础以及眼部疾病的起源。支持四个模块。 1。形态和显微镜模块将在进行激光扫描共聚焦显微镜，透射电子显微镜和光显微镜方面提供资源，服务和技术援助。 2。分子生物学模块将提供DNA测序和一般分子生物学服务和供应。此外，它将支持维护共享设备以及成像中心和组织培养设施的管理和运行。 3。计算机服务模块将为研究人员提供技术帮助，以优化用于研究目的的计算机配置，与实验室设备接口，创建和维护数据库，传输和存储大型数据和图像文件，并维护研究社区专用的服务器。它还将为该核心赠款的其他模块提供广泛的支持。 4。临床接口模块将为需要人类血液的研究计划提供帮助。它将促进淋巴细胞颗粒的制备和储存，DNA样品的制备以及维持包含与储存血液样本患者有关的临床信息的数据库。我们的部门致力于以下理念：最有效的研究计划应基于多学科方法，涉及基础科学家和临床科学家的努力。遵循强烈的机构支持的传统，该部门为本申请中讨论的研究努力保持了极好的环境。该核心赠款将提供重要的资源，以确保我们计划的持续卓越，并为进一步的教学和研究机会贡献重要的资源。