Auditory Inputs to Nucleus Interfacialis (NIf)

面间核 (NIf) 的听觉输入

• 批准号: 6836908
• 负责人: ERIC E BAUER
• 金额: $ 4.73万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-06-01 至 2006-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6836908
• 关键词: auditory discrimination; auditory feedback; auditory nuclei; auditory pathways; auditory stimulus; auditory threshold; behavioral /social science research tag; electronic recording system; ethology; learning; postdoctoral investigator; sensorimotor system; sensory mechanism; sensory signal detection; single cell analysis; songbirds; synapses; vocalization

DESCRIPTION (provided by applicant): The songbird brain is distinguished by a network of nuclei important for learned vocal control via auditory feedback and many of the neurons throughout this network respond vigorously to the auditory presentation (playback) of the bird's own song (BOS), but not to the playback of conspecific songs. The neural network mechanisms that generate these highly selective auditory responses are unknown, but identifying where they arise along the auditory pathway is important to understanding how auditory signals influence vocal learning and how auditory experience shapes neuronal response properties. This application seeks to identify the synaptic level at which song selectivity emerges and the integrative mechanisms underlying selectivity by focusing on Nucleus Interfacialis (NIf), a sensorimotor nucleus that is important to song patterning and that contains neurons that are BOS-selective. The exact nature of NIf's auditory inputs remains unclear, although there are at least three possible sources: caudal Hyperstriatum Ventrale (cHV), Field L, and Nucleus Ovoidalis. The hypotheses of this application concern where the auditory input to NIf arises and the synaptic nature of the auditory inputs to NIf.

描述（由申请人提供）：鸣禽大脑的区别是通过听觉反馈对学习的人声控制的Nuclei网络，以及整个网络中的许多神经元对鸟自己的歌曲（BOS）的听觉演示（BOS）的许多神经元的反应，但不是要播放出色的歌曲。产生这些高度选择性听觉反应的神经网络机制尚不清楚，但是识别它们沿听觉途径的何处对于理解听觉信号如何影响声音学习以及听觉经验如何塑造神经元反应属性很重要。该应用程序旨在确定歌曲选择性出现的突触水平以及通过关注核核核（NIF）（NIF）的综合机制，这是一种对歌曲图案很重要的感觉运动核，其中包含BOS-选择性的神经元。 NIF听觉输入的确切性质尚不清楚，尽管至少有三个可能的来源：尾侧纹状体（CHV），田间L和Ovoidalis。该应用程序的假设涉及到NIF的听觉输入以及听觉输入到NIF的突触性质。