Enhanced Power for Assisted Blood Circulation

增强辅助血液循环的能力

• 批准号: 6549506
• 负责人: John J Bowser
• 金额: $ 10万
• 依托单位: COMPACT MEMBRANE SYSTEMS, INC.
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-08-01 至 2004-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6549506
• 关键词: artificial membranes; auxiliary heart prosthesis; bioengineering /biomedical engineering; biomedical device power system; biomedical equipment development; circulatory assist; energy source; oxygen transport; polymers; total artificial organ; zinc

DESCRIPTION (provided by applicant): Total Artificial Heart (TAH) and related devices (e.g., ventricular assist device) are emerging that provide the potential for almost unlimited patient mobility and near-normal lifestyle for the patient. The new devices being developed are totally implantable, self-contained (battery is external), electrically driven systems. However, the power and energy density requirements of the new devices are high and in many cases exceed the best battery technology available today. The proposed research in this program seeks to develop novel primary batteries with three times the energy density of existing primary batteries. In Phase I we will demonstrate feasibility of enhanced battery components and obtain participation of major battery manufacturer. In Phase II we will integrate enhanced battery components into prototype battery and demonstrate improved performance compared to conventional batteries. In Phase I we will demonstrate feasibility of enhanced battery components as well as enhanced performance of laboratory batteries. In Phase II we will integrate enhanced battery components into prototype batteries and in field tests demonstrate improved performance compared to controls. Both phase I and Phase II programs will be enhanced by our recent addition of both commercial battery partner and commercial blood pump expert.

描述（由申请人提供）：全人工心脏（TAH）和相关装置（例如心室辅助装置）正在兴起，为患者提供几乎无限的活动能力和接近正常的生活方式。正在开发的新设备是完全可植入的、独立的（电池在外部）、电力驱动系统。然而，新设备的功率和能量密度要求很高，在许多情况下超过了当今最好的电池技术。该计划拟议的研究旨在开发新型原电池，其能量密度是现有原电池的三倍。在第一阶段，我们将展示增强电池组件的可行性，并获得主要电池制造商的参与。在第二阶段，我们将把增强的电池组件集成到原型电池中，并展示与传统电池相比改进的性能。在第一阶段，我们将展示增强电池组件的可行性以及增强实验室电池的性能。在第二阶段，我们将把增强的电池组件集成到原型电池中，并在现场测试中证明与对照相比性能得到改善。我们最近增加了商业电池合作伙伴和商业血泵专家，第一阶段和第二阶段计划都将得到加强。