CORE--IMAGING

核心--成像

• 批准号: 6932956
• 负责人: Richard E Waugh
• 金额: $ 6.92万
• 依托单位: UNIVERSITY OF ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-07-01 至 2009-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6932956
• 关键词: bioimaging /biomedical imaging; biomedical facility; computer program /software; computer simulation; confocal scanning microscopy; flow cytometry; fluorescence microscopy; image processing; video microscopy; video recording system

Image acquisition, image processing, image analysis, and detection and interpretation of fluorescence signals are fundamental tools used in all of the projects. The availability of hardware and software to accomplish these tasks, and the availability of technical support to maintain and improve existing capabilities and to develop new processing methodologies is essential for the effective and timely completion of the proposed studies. The core includes support for confocal microscopy, flow cytometry, and support for the purchase of hardware to be used for video image processing and the development of software to facilitate extraction of information from experimental images. In addition, in the current application we propose to expand core capabilities to include Total Internal Reflectance Fluorescence Microscopy (TIRFM). Projects 2, 3 and 5 are developing new research directions that will benefit from this resource, and the remaining two projects, to a lesser extent, will benefit from the availability of these capabilities.

图像采集、图像处理、图像分析以及荧光信号的检测和解释是所有项目中使用的基本工具。完成这些任务的硬件和软件的可用性，以及维持和提高现有能力以及开发新的处理方法的技术支持的可用性对于有效和及时完成拟议的研究至关重要。核心包括对共焦显微镜、流式细胞术的支持，以及对购买用于视频图像处理的硬件和开发软件以促进提取的支持。 来自实验图像的信息。此外，在当前的应用中，我们建议扩展核心功能，包括全内反射荧光显微镜（TIRFM）。项目 2、3 和 5 正在开发新的研究方向，这些方向将受益于该资源，而其余两个项目将在较小程度上受益于这些能力的可用性。