EXTRAMURAL RESEARCH FACILITIES CONSTRUCTION

校外研究设施建设

基本信息

批准号：
6706109
负责人：
John R Raymond
金额：
$ 285.43万
依托单位：
MEDICAL UNIVERSITY OF SOUTH CAROLINA
依托单位国家：
美国
项目类别：
财政年份：
2003
资助国家：
美国
起止时间：
2003-09-15 至 2008-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/6706109
关键词：
biomedical facility cell sorting children chronic disease /disorder developmental neurobiology tissue engineering training university

项目摘要

DESCRIPTION (provided by applicant): This is a new application requesting $3,171,444 from National Center for Research Resources (NCRR) to complete shelled space on two floors of the Children's Research Institute (CRI) a 121,000 sq. ft, laboratory building under construction adjoining the Basic Science Building (BSB). The completion of the fifth and sixth floors as proposed will create space to: 1) serve as the physical center for two multi-departmental, interdisciplinary research programs in developmental neuroscience and cardiovascular developmental biology; 2) establish cutting-edge core facilities in lipidomics, cell sorting, tissue engineering, and histology to maintain and expand PHS-supported research; 3) facilitate and foster more biomedical research and training of both physician scientists and basic scientists throughout MUSC who can gain experience and understanding of the molecular and genetic basis of diseases and disorders of childhood and development. The research addresses national priorities in children's health and diseases, normal development, and chronic diseases that may have a fetal or early developmental origin as part of their pathogenesis. The proposed project will address three major deficiencies in research space at MUSC: 1) inadequate and dysfunctional research space, 2) space constraints, and 3) dispersion of core resources. The primary beneficiaries are faculty members from four departments (Pediatrics, Neurology, Biochemistry, and Cell Biology), as well as students, postdoctoral fellows, and collaborators. The project will facilitate the recruitment of a neurobiologist with expertise in neuronal cell lineage development, a senior molecular biologist and human geneticist, a stem cell biologist, and one or more tissue engineer(s) with expertise in biomatrices and/or bioreactors. The total project cost is $6,342,887; the University is contributing $3,171,443 (50 percent).

描述（由申请人提供）：这是一个新的申请，要求来自国家研究资源中心（NCRR）的3,171,444美元，以在儿童研究所（CRI）（CRI）的两层上完成炮击空间，该空间为121,000平方英尺，毗邻基础科学大楼（BSB）的实验室大楼（BSB）。拟议的第五层和第六层的完成将为以下空间创造：1）作为发展性神经科学和心血管发育生物学的两个多部门跨学科研究计划的物理中心； 2）在脂质组学，细胞分选，组织工程和组织学方面建立最先进的核心设施，以维持和扩展受PHS支持的研究； 3）在MUSC的整个MUSC的医师科学家和基础科学家中促进并促进并培养更多的生物医学研究，并培训可以获得疾病和童年和发育疾病的分子和遗传基础的经验和理解。该研究涉及儿童健康和疾病，正常发育以及可能具有胎儿或早期发育起源的慢性疾病的国家优先事项。拟议的项目将解决MUSC研究空间中的三个主要缺陷：1）不足和功能失调的研究空间，2）空间限制和3）核心资源的分散。主要受益人是来自四个部门（儿科，神经病学，生物化学和细胞生物学）的教职员工，以及学生，博士后研究员和合作者。该项目将促进具有神经元细胞谱系发育专业知识的神经生物学家，一名高级分子生物学家和人类遗传学家，干细胞生物学家，以及一名或多名或多个组织工程师，具有在生物学和/或生物反应器方面的专业知识。项目总成本为6,342,887美元；该大学贡献了3,171,443美元（50％）。