THE BOSTON HAPPENS ADOLESCENT MEDICINE TRIALS UNIT

波士顿青少年医学试验中心

• 批准号: 6637417
• 负责人: CATHRYN L SAMPLES
• 金额: $ 122.35万
• 依托单位: BOSTON CHILDREN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-04-16 至 2006-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6637417
• 关键词: AIDS; AIDS /HIV diagnosis; AIDS /HIV test; AIDS education /prevention; AIDS therapy; HIV infections; adolescence (12-20); clinical trials; cooperative study; counseling; disease /disorder proneness /risk; health behavior; health care referral /consultation; human subject; human therapy evaluation; information dissemination; longitudinal human study; medical outreach /case finding; patient oriented research; pediatric AIDS; sex behavior; social service; substance abuse related disorder; urban area; young adult human (21-34)

The numbers of adolescents living with HIV/AIDS continue to rise in the United States with more children with perinatally transmitted HIV increasing surviving to the adolescent and young adult years. Metropolitan Boston has been greatly impacted by HIV/AIDS and has followed the national trends of increasing numbers of young women, young men who have sex with men, and youth of color. The Boston HAPPENS' (Boston HIV Provider and Peer Education Network for services) Adolescent Medicine Trials Unit (AMTU) has been developed to provide access to clinical trials and research for young people 12-24 years old in the metropolitan area. The AMTU is housed in the Adolescent/Young Adult Division, Children's Hospital, Boston, with a single team of adolescent- specific HIV care providers who will offer services at Children's Hospital, Boston Medical Center and the Sydney Borum, Jr, Health Center. Children's Hospital and Boston Medical Center serve diverse populations including youth of color, young women, perinatally infected youth and gay/bisexual youth in their Adolescent Practices. The Sydney Borum, Jr., Health Center particularly provides care to gay/bisexual and transgender youth and street involved youth. The broad collaborative network of the Boston HAPPENS Program allows for the ongoing connection for young people to receive care in adolescent settings. The specific aims of this project are to: 1) recruit and retain 75 HIV infected youth for ATN studies, 2) recruit and retain 125 appropriate controls, 3) participate in the development of the ATN research agenda, 4) establish expert and community advisory boards, and 5) strengthen HIV care and research efforts in metro-Boston. We currently have 71 HIV positive (12-23 years old, 60% female old, 60% female, 75% black) in care, project by July 1, 2000 that will have 90 HIV positive as well as 125 control subjects. Our long term experience with the Pediatric AIDS Clinical Trials Group (PACTG), the Adolescent PACTG initiative, and the Boston HAPPENS Program allow us to have access to large numbers of adolescents and extensive experience with HIV care, treatment regimens, research, and clinical trials protocols. In addition, we look forward to working closely with the existing research network and the Adolescent Medicine Trials Network to help develop the scientific agenda for adolescents and young adults.

在美国，患有艾滋病毒/艾滋病的青少年的人数继续增加，围产期传播的艾滋病毒的儿童增加，使成年和年轻人的生存增加。 波士顿大都会受到艾滋病毒/艾滋病的极大影响，并遵循了越来越多的年轻妇女，与男人发生性关系的年轻男性和有色人种的年轻男性的趋势。 波士顿发生了（波士顿的艾滋病毒提供者和服务服务网络）青少年医学试验部（AMTU）已开发出来，为在大都市地区12-24岁的年轻人提供临床试验和研究的访问权限。 AMTU位于波士顿儿童医院的青少年/年轻成人部门，由一支由青少年特定的艾滋病毒护理提供者组成的团队，他们将在波士顿医疗中心和卫生中心的儿童医院和悉尼博罗姆（Sydney Borum）提供服务。儿童医院和波士顿医疗中心为各种各样的人群提供服务，包括有色人种，年轻妇女，围产期感染的青年和同性恋/双性恋青年的青少年实践。 小悉尼博罗姆（Sydney Borum）卫生中心特别为年轻人提供了同性恋/双性恋和变性青年和街道的照顾。 波士顿发生的广泛协作网络允许年轻人在青少年环境中获得护理的持续联系。 该项目的具体目的是：1）招募和保留75名HIV感染的ATN研究青年，2）招募和保留125个适当的控制，3）参与ATN研究议程的发展，4）建立专家和社区咨询委员会，以及5）5）在Metro-Boston在Metro-Boston中的HIV护理和研究工作。 目前，我们有71个HIV阳性（12-23岁，女性60％，女性60％，黑色为75％），到2000年7月1日之前，他们将拥有90个HIV阳性和125名对照对象。 我们在小儿艾滋病临床试验组（PACTG），青少年pactg倡议和波士顿发生的长期经验，使我们能够获得大量的青少年，并获得了HIV护理，治疗方案，研究和临床试验方案的丰富经验。 此外，我们期待与现有的研究网络和青少年医学试验网络紧密合作，以帮助为青少年和年轻人开发科学议程。