CORE--TECHNOLOGY

核心技术

• 批准号: 6651747
• 负责人: TIMOTHY J JORGENSEN
• 金额: $ 34.88万
• 依托单位: GEORGETOWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-01 至 2007-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6651747
• 关键词: X ray; atomic force microscopy; biomedical equipment resource; biomedical facility; gamma radiation; ionizing radiation; microarray technology; neoplasm /cancer radiation therapy; statistics /biometry

DESCRIPTION (provided by applicant): The technology core supports the common technical needs of all of the projects within the Program Project. Support includes readily available experimental instrumentation, technical advice and expertise in the use of instruments, technical assistance in conducting experiments, and assistance in experimental design and interpretation of data. The Core consists of four separate facilities: Radiation: Provides the gamma- and x-ray instruments for cell and animal irradiations. AFM: Provides atomic force microscopy services for imaging biological macromolecules. Microarray: Provides automated chip and database equipment for measuring gene expression levels in cells. Biostatistics: Provides statistical assistance for experimental design and data analysis. Dr. Timothy Jorgensen is the Director of the Technology Core. He coordinates and oversees all the activities of the Core, including financial and administrative functions, as well as supervises the individual Facility Directors. He monitors established policies that govern the fair and equitable use of the facilities among the various projects, and prioritizes facility usage in the best interests of the overall Program. He will track usage of the facilities, ensuring that they are well maintained and kept in working order, resolve user disputes, insure compliance with safety regulations, and provide an annual report on the status of the Core to the Program Project Director.

描述（由申请人提供）：技术核心支持计划项目中所有项目的共同技术需求。支持包括随时可用的实验仪器，技术建议和专业知识，用于使用仪器，进行实验的技术援助以及实验设计和数据解释的帮助。核心由四个独立的设施组成：辐射：为细胞和动物辐射提供伽马和X射线仪器。 AFM：提供用于成像生物大分子的原子力显微镜服务。微阵列：提供自动芯片和数据库设备，用于测量细胞中的基因表达水平。生物统计学：为实验设计和数据分析提供统计辅助。蒂莫西·乔根森（Timothy Jorgensen）博士是技术核心的主任。他协调并监督核心的所有活动，包括财务和行政职能，并监督各个设施董事。他监督制定政策，以在各个项目中公平且公平地使用设施，并将设施使用优先级使用，以符合整体计划的最大利益。他将跟踪设施的使用情况，确保它们保持良好的维护和保持工作状态，解决用户纠纷，确保遵守安全法规，并向计划项目主管提供有关核心状况的年度报告。