CORE--RADIATION FACILITY

核心--辐射设施

• 批准号: 6237799
• 负责人: TIMOTHY J JORGENSEN
• 金额: $ 19.46万
• 依托单位: GEORGETOWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-06-27 至 1998-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6237799
• 关键词: X ray; biomedical equipment purchase; biomedical equipment resource; biomedical facility; ionizing radiation; neoplasm /cancer radiation therapy

The Radiation Core will provide the irradiation in support of all of the projects in the program. This core is housed in the Lombardi Cancer Center and currently consists of a J.L Shepard Mark I, Model 30, Cesium Irradiator. This Mark I is specifically designed for experimental gamma-irradiations. It contains a 2,200 Ci 137 Cs source. Tissue culture flasks are irradiated by stacking them on the rotating platform. A special rotating tube holder can accommodate test tubes with volumes up to 50 ml. A pie-shaped rotating mouse holder allows simultaneous whole-body irradiations of a dozen mice at a time. The cesium irradiator is suitable for the majority of the irradiations required by this program; however, the inability to effectively focus and block the beam makes it difficult to use the instrument for partial body irradiations, such as tumor irradiations in the flanks of mice. Also, the penetrability of the radiation cannot be controlled because the photon energy cannot be modulated. For these reasons, we are requesting the purchase of a low cost, portable, x-ray machine, that cannot be dedicated to the experimental work of the program. The requested x-ray machine is the RS2000, manufactured by Rad-Source, a division of Microfocus Imaging, Inc of Wheeling, IL. Dr. Timothy Jorgenson is Director of the Radiation Core. His responsibilities include training personnel in the proper and safe use of the instruments, and ensuring compliance with NRC regulations. Dr. Jorgenson chairs an Internal Advisory Committee. The Committee meets as needed to set rules and policies from instrument use, and to make decisions concerning maintenance and repairs. The committee guarantees fair and equitable use of the instruments among the investigators.

辐射芯将提供支持所有人的辐射 计划中的项目。该核心位于伦巴第 癌症中心，目前由J.L Shepard Mark I组成 30，铯辐照器。我专门为此而设计的标记 实验性γ-辐射。它包含2200 CI 137 CS 来源。 组织培养瓶通过将其堆叠在 旋转平台。一个特殊的旋转管支架可以 可容纳高达50毫升的测试管。一个派形 旋转的鼠标支架允许同时进行全身辐照 一次一次。 Cesium辐照器适合 该计划所需的大部分辐射；但是， 无法有效聚焦和阻挡光束使它变得困难 将仪器用于部分身体辐射，例如肿瘤 小鼠侧面的辐照。另外， 辐射无法控制，因为光子能不能是 调制。由于这些原因，我们要求购买 低成本，便携式，X射线机，不能专用于 该计划的实验工作。请求的X射线机是 RS2000，由Rad-Source制造，微聚焦的一个部门 成像，惠灵公司，伊利诺伊州。 Timothy Jorgenson博士是 辐射芯。他的责任包括培训人员 适当，安全地使用乐器，并确保 遵守NRC法规。 Jorgenson博士椅子内部 咨询委员会。委员会根据需要开会，以制定规则和 仪器使用的政策，并做出有关 维护和维修。委员会保证公平，公平 在调查人员中使用仪器。