Supplemental kentucky Bioinformatics Research infrastru*

补充肯塔基州生物信息学研究基础设施*

• 批准号: 6588340
• 负责人: NIGEL G.F. COOPER
• 金额: $ 108.88万
• 依托单位: UNIVERSITY OF LOUISVILLE
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-30 至 2004-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6588340
• 关键词: education evaluation /planning; genetics; health science research; health science research potential; informatics; information dissemination; interdisciplinary collaboration; molecular biology information system; science education; training

DESCRIPTION (provided by applicant): The principal goal of this supplement to the NIH-BRIN proposal is to develop a statewide science research core (SRC). The SRC will provide the impetus to build capacity for research activities within the framework of the existing KBRIN. The SRC will consist of a set of research projects. This will entail an expansion of KBRIN to include new faculty and student participation. To maximize the leveraging potential of institutional assets and resources these two sub-cores will emphasize strengths in the research-intensive and comprehensive institutions respectively. A neuroscience focus will make use of emerging strengths of the two research-intensive institutions, the University of Louisville (UL) and the University of Kentucky (UK), to encourage collaborations and training in their numerous research-active laboratories. This sub-core will allow us to draw researchers from the comprehensive institutions into one of the larger basic-biomedical research endeavors within the state, and it will provide us the opportunity to build additional capacity in this discipline. The second sub-core will provide a population biology focus, and this will make use of existing faculty strengths in biology departments of the ten comprehensive and primarily undergraduate institutions that are KBRIN-partners. This will help us to engage a larger number of undergraduate students in the process of discovery than could otherwise be accomplished. The objective will be to attract students, mostly from rural backgrounds, into the principles and practices of research, while engaged in exciting projects in field biology. Support for six new research projects in each of these two sub-cores is requested in this application. The application of genomics and bioinformatics tools and methods are common elements of these two sub-cores. Therefore, the existing KBRIN- administrative, mentoring/training, genomics and bioinformatics cores will be major players in the development and implementation of the SRC, and will provide a supporting role to insure the success of the research projects. The outcome of adding the SRC will be a sharper research focus for the KBRIN. This will provide a stronger partnership and multi-institutional commitment to the development of biomedical research and education in the Commonwealth of Kentucky.

描述（由申请人提供）：NIH-Brin提案补充的主要目标是开发全州科学研究核心（SRC）。 SRC将提供在现有KBRIN框架内建立研究活动能力的动力。 SRC将由一组研究项目组成。 这将需要扩大KBRIN，包括新的教职员工和学生参与。 为了最大程度地提高机构资产和资源的潜在利用，这两个子核将分别强调研究密集型和全面的机构中的优势。 神经科学的重点将利用两个研究密集型机构路易斯维尔大学（UL）和肯塔基大学（英国）的新兴优势，以鼓励在众多研究活性实验室中进行合作和培训。 该子核心将使我们能够将研究人员从综合机构中吸引到该州内部较大的基本生物医学研究努力之一，这将为我们提供在该学科中建立额外能力的机会。 第二个子核心将提供人口生物学的重点，这将利用十个综合和主要是Kbrin-Partners的综合机构的生物学部门的现有教师优势。 这将有助于我们参与发现的更多本科生，而不是其他方法。 目的是将主要来自农村背景的学生吸引研究的原则和实践，同时从事现场生物学的令人兴奋的项目。 在本应用程序中要求对这两个子核的六个新研究项目的支持。 基因组学和生物信息学工具和方法的应用是这两个子核的常见元素。 因此，现有的KBRIN-行政，指导/培训，基因组学和生物信息学核心将是SRC开发和实施的主要参与者，并将提供支持角色，以确保研究项目的成功。 添加SRC的结果将是KBRIN的更加研究重点。 这将为肯塔基州联邦的生物医学研究和教育的发展提供更强大的伙伴关系和多机构的承诺。