Neuropeptide Modulation of Social Behaviors

社会行为的神经肽调节

• 批准号: 6694923
• 负责人: NICHOLAS SANTANGELO
• 金额: $ 3.97万
• 依托单位: CORNELL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-08-01 至 2006-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6694923
• 关键词: aggression; animal communication behavior; animal ecology; arginine vasopressin; behavior test; behavioral /social science research tag; fish; immunocytochemistry; in situ hybridization; neuroendocrine system; neuropsychology; neuroregulation; postdoctoral investigator; protein localization; reproduction; sex behavior; social behavior; vasotocin; vocalization

DESCRIPTION (provided by applicant): This proposal focuses on the neuroendocrine mechanisms determining social and reproductive behaviors among vertebrates. Across different classes of vertebrates, the neuropeptide arginine vasotocin (AVT), as well as its mammalian homologue arginine vasopressin (AVP), play a key role in the regulation of complex male social behaviors such as aggression, courtship, and vocalizations associated with these behaviors. Many studies indicate that AVT/AVP's role in modulating these behaviors is a function of the social system of the species in question, however there is evidence that individual status within a social system also plays a part in determining the directionality of AVT/AVP's influences, i.e. either facilitating or inhibiting behavior. Few studies focus on the interaction between environment and hormone function in the expression of individual behavior. Among beaugregory damselfish, males exhibit different levels of aggression and courtship based upon their territory quality. The overall goal of this proposal is to identify how AVT- interacts with an individual's ecology (i.e. territory quality) to modulate aggression, courtship, and the vocalizations associated with these behaviors.

描述（由申请人提供）：该提案着重于决定脊椎动物中社会和生殖行为的神经内分泌机制。在不同类别的脊椎动物，神经肽精氨酸血管素（AVT）及其哺乳动物同源性精氨酸加压素（AVP）中，在调节复杂的男性社会行为（例如侵略，求爱，宫廷和嗓音）中起着关键作用。许多研究表明，AVT/AVP在调节这些行为中的作用是所讨论的物种社会系统的函数，但是有证据表明，社会系统中的个人地位也在确定AVT/AVP影响的方向上起着作用，即促进或抑制行为。很少有研究重点是环境与激素在个体行为表达中的相互作用。在Beaugregory Damellish中，雄性根据其领土质量表现出不同程度的侵略和求爱。该提案的总体目标是确定AVT与个人的生态学（即领土质量）相互作用，以调节侵略，求爱和与这些行为相关的发声。