CORE--RADIOLOGICAL SCIENCES

核心--放射科学

• 批准号: 6664428
• 负责人: WILLIAM C COLE
• 金额: $ 25.04万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-05-06 至 2003-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6664428
• 关键词: antitumor antibody; biomedical facility; monoclonal antibody; neoplasm /cancer radioimmunotherapy

Description: (Applicant's Description) The Radiological Sciences core was one of the original cores established at the inception of the University of Colorado Cancer Center in 1988 to provide centralized facilities, training, and expertise for cancer research involving the use of ionizing radiation including irradiation facilities, preparation of radiolabeled cells and antibodies for cancer diagnosis and treatment, radiation dosimetry, and diagnostic imaging consultation services. Cancer center member usage of the60 Co irradiator has been stable over the last five years and has increased by about 50% for 1999. Radiolabeling services have been used primarily for monoclonal antibody labeling for radioimmunotherapy. This function is projected to increase due to the FDA approval of new antibodies and recruitment of new faculty. Dosimetry consultation services have focused on radiolabeled monoclonal antibodies for radioimmunotherapy as well. The transition to our new campus at Fitzsimons is expected to increase the need for additional facilities for irradiation as Cancer Center members move their research activities to the new site. In addition, the new cyclotron and PET capabilities are expected to increase research opportunities and the involvement of the Radiological Sciences core.

描述：（申请人的描述）放射科学核心是一 大学成立时建立的原始核心 科罗拉多癌症中心于1988年提供集中设施、培训、 以及涉及使用电离辐射的癌症研究的专业知识 包括辐照设施、放射性标记细胞的制备和 用于癌症诊断和治疗、放射剂量测定的抗体，以及 诊断影像咨询服务。癌症中心会员使用 the60 联合辐照器在过去五年中一直稳定，并且增加了 1999 年约为 50%。放射性标记服务主要用于 用于放射免疫治疗的单克隆抗体标记。这个函数是 由于 FDA 批准新抗体和 招聘新教师。剂量测定咨询服务重点关注 放射性标记的单克隆抗体也用于放射免疫治疗。这 过渡到菲茨西蒙斯新校区预计会增加需求 当癌症中心成员移动他们的身体时，需要额外的照射设施 研究活动转移到新地点。此外，新型回旋加速器和 PET 预计能力将增加研究机会和 放射科学核心的参与。