COMBINED VISUAL DISPLAY & EYE TRACKING SYSTEM FOR HIGH FIELD FMRI STUDIES

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• 批准号: 6480907
• 负责人: Paul Douglas Gamlin
• 金额: $ 15.58万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-08-01 至 2003-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6480907
• 关键词: bioengineering /biomedical engineering; biomedical resource; cognition; communication behavior; magnetic resonance imaging; nervous system

An open question in our understanding of language processing and speech production is whether a common phonological lexicon within the brain serves both speech production and word recognition. Data from studies of patients with lesions provide conflicting evidence about the neural substrates mediating phonological access, supporting both the common lexicon and dual lexicons hypotheses. fMRI studies using Echo-planar imaging (EPI) will be performed in 10 right-handed subjects. Our fMRI study uses tasks that systematically evaluate both input and output phonological processing, and should help resolve the uncertainty about the number of phonological lexicons and their structure and function. Four tasks will be applied in these studies: Auditory discrimination, Rhyme judgments, Lexical decisions, and Synonym judgments. The project is funded by an NIH R03 (1/01/98 to 12/31/98). Preliminary studies have been performed to verify the operation of the auditory stimulus hardware. The initial studies performed in this project will likely lead to more comprehensive studies in the future. This research may result in a better understanding of the brain pathways involved in phonological access for speech production and for word recognition, and may contribute to a better understanding of language development and disorders.

我们对语言处理和理解的理解存在一个悬而未决的问题 语音生成是指语言中是否存在共同的语音词汇 大脑既服务于语音生成，又服务于单词识别。 数据来自 对病变患者的研究提供了相互矛盾的证据 介导语音通路的神经基质，支持两者 共同词典和双重词典假设。 使用平面回波成像 (EPI) 的功能磁共振成像研究将在 10 个右手受试者。 我们的功能磁共振成像研究使用的任务 系统地评估输入和输出语音处理， 并应有助于解决数量的不确定性 语音词典及其结构和功能。 四项任务 将应用于这些研究：听觉辨别、押韵 判断、词汇判断和同义词判断。 该项目由 NIH R03（1/01/98 至 12/31/98）资助。 已进行初步研究以验证该装置的运行情况 听觉刺激硬件。 该项目中进行的初步研究可能会导致 未来将进行更全面的研究。 这项研究可能会导致 更好地理解涉及语音的大脑通路 访问语音生成和单词识别，并且可以 有助于更好地理解语言发展和 失调。