Quantitative Trait Loci for Reproductive Behavior

生殖行为的数量性状基因座

• 批准号: 6445732
• 负责人: AMANDA J MOEHRING
• 金额: $ 2.36万
• 依托单位: NORTH CAROLINA STATE UNIVERSITY RALEIGH
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-05 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/6445732
• 关键词: Drosophilidae; behavioral /social science research tag; behavioral genetics; ethology; gene complementation; gene expression; genetic mapping; genetic markers; genetic polymorphism; genetic recombination; genetic strain; genotype; quantitative trait loci; sex behavior; species difference; Drosophilidae; behavioral /social science research tag; behavioral genetics; ethology; gene complementation; gene expression; genetic mapping; genetic markers; genetic polymorphism; genetic recombination; genetic strain; genotype; quantitative trait loci; sex behavior; species difference

DESCRIPTION (provided by applicant): The general aim of this project is to determine the molecular and quantitative genetic basis of mating behavior in Drosophila. The specific aims are to map with high resolution the quantitative trait loci (QTL) responsible for intra-specific variation in courtship initiation time and time to copulation in Drosophila melanogaster; and to map QTL associated with pre-zygotic reproductive isolation between D. mauritiana and D. simulans. Previously, I mapped QTL responsible for variation in male mating behavior between two D. melanogaster strains. Deficiency and recombination mapping will be used to map these QTL with high resolution, and complementation testing will be used to identify candidate genes responsible for naturally occurring variation in behavior. The number, map positions and effects of QTL responsible for ethological divergence between species will be determined by associating mating behavior with polymorphic molecular markers in interspecific backcross hybrids.

描述（由申请人提供）：该项目的一般目的是 确定交配行为的分子和定量遗传基础 果蝇。具体目的是用高分辨率映射定量 特质基因座（QTL）负责特定于求爱的特定差异 在果蝇果蝇中交配的时间和时间；并映射 QTL与D. Mauritiana之间的杂种生殖隔离相关 和D. Simulans。以前，我绘制了负责男性变化的QTL 两个D. melanogaster菌株之间的交配行为。缺陷和 重组映射将用于用高分辨率映射这些QTL，并且 互补测试将用于识别负责的候选基因 对于自然发生的行为变化。数字，地图位置和 QTL负责物种之间的伦理差异的影响将是 通过将交配行为与多态性分子标记相关联 种间杂交杂种。