RISK FACTORS FOR ATTENTION DEFICIT/HYPERACTIVITY DISORDER

注意力缺陷/多动症的危险因素

• 批准号: 6432338
• 负责人: Andrew S. Rowland
• 金额: --
• 依托单位: NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/6432338
• 关键词: alcoholic beverage consumption; attention deficit disorder; clinical research; disease /disorder etiology; disease /disorder proneness /risk; dosage; embryo /fetus toxicology; environmental health; human subject; lead poisoning; mental health epidemiology; middle childhood (6-11); premature labor; tobacco abuse

We are finishing the second and final year of data collection for the study. Data collection should end in July, 2000. We have achieved an 84% response rate from parents in the study, which is high for this type of community based study. About 98% of the 350 teachers in the study have participated and filled out information about themselves, their class, and their students. Overall, we have continued to have strong support for the study from the School Administration, from teachers and staff, and from parents. So far we have completed about 1000 interviews with parents; we hope to ultimately complete interviews on 650 cases and 650 controls. We are starting a clinical sub-study on 50 cases identified using our epidemiologic case definition. These children and their mothers will be interviewed by a clinician using a semi-structured interview and we will collect school records, teacher ratings, and psychological test results. The goal of the sub-study is to see what proportion of our cases would best be explained by another disorder if they had been seen in a physician's office with access to all the data about the child. This is an important study because ADHD is such a controversial diagnosis. I have linked our cohort files with the State lead testing registry files. We have been working with the Drug Enforcement Administration to obtain data on the distribution of stimulant use across North Carolina Counties. This will enable us to determine whether rates in Johnston County are atypical

我们即将完成该研究的第二年也是最后一年的数据收集。 数据收集应于 2000 年 7 月结束。我们在这项研究中获得了 84% 的家长答复率，这对于此类基于社区的研究来说是很高的。 参与研究的 350 名教师中，约有 98% 参与并填写了有关自己、班级和学生的信息。总体而言，我们继续得到学校行政部门、教师和工作人员以及家长对本研究的大力支持。到目前为止我们已经完成了约1000份家长访谈；我们希望最终完成对 650 个病例和 650 个对照的访谈。我们正在开始对使用我们的流行病学病例定义确定的 50 例病例进行临床子研究。 这些孩子及其母亲将接受临床医生的半结构化访谈，我们将收集学校记录、教师评分和心理测试结果。 子研究的目的是看看如果我们的病例是在医生办公室就诊并能获得有关孩子的所有数据，那么有多少比例的病例最能用另一种疾病来解释。 这是一项重要的研究，因为多动症是一个有争议的诊断。我已将我们的队列文件与州领先测试注册表文件链接起来。我们一直在与缉毒局合作，获取北卡罗来纳州各县兴奋剂使用分布的数据。这将使我们能够确定约翰斯顿县的利率是否不典型