Conference: Second Messengers & Protein Phosphorylation

会议：第二使者

• 批准号: 6369306
• 负责人: JACK E DIXON
• 金额: $ 0.5万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-06-01 至 2002-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6369306
• 关键词: meeting /conference /symposium; phosphorylation; proteins; second messengers; travel

DESCRIPTION (provided by applicant): The Gordon Research Conference (GRC) Conference on Second Messengers & Protein Phosphorylation will be held from June 10 to June 15, 2001 in Kimball Union Academy, New Hampshire. This application seeks partial support for the operation of the conference. Research in the area of signal transduction is an essential part of the investigation into how cells regulate growth, differentiation and cell death. Within the past year there have been many advances in our understanding of kinase, phosphatase and G-protein coupled signaling system. These advances include new X-ray structures for many signal components as well as functional studies defining elements within signaling cascades. In addition, there has been an explosion in our knowledge of how ion channels are modulated, the inter-connections of phosphorylation events and the use of cytoskeletal architecture to control and regulate molecular signaling events. The purpose of the meeting is to integrate biochemical, structural, cell biological and genomic approaches into providing a comprehensive understanding of the molecular aspects of signaling mechanisms. Like other GRCs, this meeting will select 135 participants from applications including representatives from industry and academia. Participants will include senior scientists, postdoctoral fellows and graduate students. There is a constant infusion of new researchers from various disciplines into the signal transduction area and the 2001 conference will be an important "training" ground for these new investigators. The conference will consist of nine sessions, each with a discussion leader and four to six speakers, selected from investigators who have made important recent contributions and from submitted abstracts. This will help to insure inclusion of young investigators, women and minorities as primal participants. Additionally two poster sessions will be organized. We have selected two keynote speakers: Alexander Varshavsky, chosen because of the increasing role of ubiquitin and ubiquantin-like protein modification in regulating signal transduction pathways, and Alfred Gilman, who has initiated efforts to form a G-protein signal transduction Alliance. This represents a new way of doing science and he will report on the progress of the Alliance and the strategies, which allow the signal transduction community to interact with the Alliance. It is important to point out that the Second Messengers and Protein Phosphorylation meeting cuts across many of the Institutes within the NIH, including Diabetes, Cancer, General Medical Sciences, Child Health and Development, as well as Immunology, to mention only a few.

描述（由申请人提供）： 戈登研究会议 (GRC) 第二信使和蛋白质会议 磷酸化将于2001年6月10日至6月15日在Kimball Union举行 学院，新罕布什尔州。本申请寻求部分支持 会议的运作。信号转导领域的研究是 研究细胞如何调节生长的重要组成部分， 分化和细胞死亡。在过去的一年里，出现了很多 我们对激酶、磷酸酶和 G 蛋白偶联的理解取得了进展 信号系统。这些进步包括用于许多信号的新 X 射线结构 成分以及功能研究定义了信号传导中的元素 级联。此外，我们对离子如何运作的了解也呈爆炸式增长。 通道被调节，磷酸化事件和 利用细胞骨架结构来控制和调节分子信号传导 事件。会议的目的是整合生物化学、结构、 细胞生物学和基因组方法提供全面的 了解信号机制的分子方面。和其他人一样 GRC，本次会议将从申请中选出 135 名与会者，包括 来自工业界和学术界的代表。参加者将包括高级 科学家、博士后研究员和研究生。有一个常数 将来自不同学科的新研究人员注入信号中 转导领域和2001年的会议将是一次重要的“培训” 这些新调查人员的基础。会议将由九名 每场会议都有一名讨论主持人和四到六名发言者，发言者选自 最近做出重要贡献的研究人员以及提交的 摘要。这将有助于确保年轻研究人员、女性和 少数民族作为主要参与者。另外还将举办两场海报展示会 有组织的。我们选择了两位主讲人：Alexander Varshavsky，选择 由于泛素和泛素样蛋白的作用日益增强 调节信号转导途径的修饰，以及阿尔弗雷德·吉尔曼（Alfred Gilman） 已发起组建G蛋白信号转导联盟的努力。这 代表了一种新的科学研究方式，他将报告该领域的进展 联盟和策略，使信号转导界能够 与联盟互动。需要指出的是，第二 信使和蛋白质磷酸化会议跨越了许多领域 NIH 内的研究所，包括糖尿病、癌症、普通医学 科学、儿童健康与发展以及免疫学等等 几个。