Conference Support: NHP Models of Aging

会议支持：NHP 老龄化模型

• 批准号: 6360663
• 负责人: Joseph W. Kemnitz
• 金额: $ 2.29万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-06-15 至 2002-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6360663
• 关键词: Callithricidae; Macaca fascicularis; Macaca mulatta; Pan; Primates; Saimiri; aging; baboons; biological models; meeting /conference /symposium

This conference grant application (R13) requests support for planning, organizing, publicizing, and hosting a special workshop entitled, "Nonhuman Primate Models of Aging: Their Current Status and Future Potential." The workshop will be held May 31-June 1, 2001, at the Monona Terrace Convention Center in Madison, Wisconsin, and will be hosted by the Wisconsin Regional Primate Research Center (WRPRC), University of Wisconsin-Madison. The workshop will be held as a satellite event to the 30th annual meeting of the American Aging Association (AGE) to be convened June 2-4, 2001, at the same location. The AGE meeting will also include a special meeting and presentations by grantees of the American Federation for Aging Research (AFAR). The objective of the workshop proposed herein is to promote an exchange of information among researchers who use various species of nonhuman primates to model age-related disease and functional decline. The meeting will be organized across 1.5 days. On the afternoon of May 31, the session will consist of presentations on microcebus (Microcebus murinus), marmosets (Callithrix jacchus), squirrel monkeys (Saimiri sciureus), cynomolgus monkeys (Macaca fascicularis), baboons (Papio hamadryas), and chimpanzees (Pan troglodytes). A working dinner will be held on the evening of May 31. Because the vast majority of research in this area has been conducted in rhesus monkeys (Macaca mulatta), the entire second day will focus exclusively on studies using this species- The morning session will include presentations on reproductive, cardiovascular, and sensory function, the skeletal system, sarcopenia, oxidative stress, glucose regulation and diabetes. The afternoon session on June 1 will focus on neurobiological and behavioral studies of aging rhesus monkeys. A poster session will be held on the evening of June 1. Research concerning nonhuman primate models of aging has shown marked growth over the last decade. Continued progress requires cooperative and integrative approaches, because the relatively long lives of primates increase the time, as well as increase the cost, required for longitudinal studies. This workshop will permit investigators to learn about the research of others in the area and to engage in productive discussion, and it will promote collaborative studies. Holding the workshop as a satellite to the AGE meeting will provide extra benefits. Members of the workshop will be encouraged to attend the AGE meeting to learn about broad areas of gerontological research that might be relevant to their nonhuman primate studies. In addition, scientists planning to attend the AGE meeting will be invited to attend the workshop to learn about the growing value of nonhuman primates for gerontological research. The location in Madison is also beneficial because it will permit the dozens of scientists and students at the University of Wisconsin and the WRPRC who are interested in aging research to attend the workshop. A final objective of the workshop is to provide attendees information on the development of the Primate Aging Database (PAD), which is a joint project of the WRPRC, the National Center for Research Resources, and the National Institute on Aging. Attendees will be given a demonstration of the software for PAD and will be encouraged to participant in the project.

该会议赠款申请（R13）要求支持计划，组织，宣传和举办一个特殊的研讨会，题为“衰老的非人类灵长类动物模型：他们的当前状态和未来潜力”。研讨会将于2001年5月31日至6月1日在威斯康星州麦迪逊市的Monona Terrace会议中心举行，并将由威斯康星大学麦迪逊大学麦迪逊大学的威斯康星州地区灵长类动物研究中心（WRPRC）主持。该研讨会将作为卫星事件举行，举行，将于2001年6月2日至4日在同一地点召集美国老龄化协会（年龄）的第30届年度会议。年龄会议还将包括美国衰老研究联合会（AFAR）的特殊会议和演讲。本文提出的研讨会的目的是促进使用各种非人类灵长类动物的研究人员之间的信息交换，以模拟与年龄相关的疾病和功能下降。会议将在1.5天内组织。 On the afternoon of May 31, the session will consist of presentations on microcebus (Microcebus murinus), marmosets (Callithrix jacchus), squirrel monkeys (Saimiri sciureus), cynomolgus monkeys (Macaca fascicularis), baboons (Papio hamadryas), and chimpanzees (Pan troglodytes).由于这一领域的绝大多数研究是在恒河猴（Macaca Mulatta）进行的，因此整个第二天将专门用于使用该物种的研究 - 早晨会议将包括有关生殖，心血管造效，骨骼系统，骨骼系统，肌脱落型，氧化应有的，氧化应力和氧化应有。 6月1日的下午会议将重点介绍衰老恒河猴的神经生物学和行为研究。海报会议将于6月1日晚上举行。关于非人类的灵长类动物衰老模型的研究表明，在过去十年中，增长了明显的增长。持续的进步需要合作和综合方法，因为灵长类动物的相对较长的寿命增加了时间，并增加了纵向研究所需的成本。该研讨会将允许调查人员了解该地区其他人的研究并进行富有成效的讨论，并将促进协作研究。将研讨会作为卫星举行到年龄会议将提供额外的好处。将鼓励研讨会的成员参加年龄会议，以了解可能与非人类灵长类动物研究相关的老年学研究领域。此外，计划参加年龄会议的科学家将邀请参加研讨会，以了解非人类灵长类动物在老年学研究中的增长价值。麦迪逊的地点也很有益，因为它将允许威斯康星大学和WRPRC的数十名科学家和学生参加老龄化研究，以参加研讨会。研讨会的最终目的是为参加者提供有关灵长类动物老化数据库（PAD）开发的信息，该项目是WRPRC，国家研究资源中心和国家老龄化研究所的联合项目。将向与会者展示PAD软件的演示，并鼓励参与该项目的参与者。