CORE--PRIMATE

核心——灵长类

基本信息

批准号：
6201410
负责人：
Ronald C Desrosiers
金额：
$ 11.68万
依托单位：
UNIV OF MASSACHUSETTS MED SCH WORCESTER
依托单位国家：
美国
项目类别：
财政年份：
1999
资助国家：
美国
起止时间：
1999-09-01 至 2000-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/6201410
关键词：
Callithricidae Macaca fascicularis Macaca mulatta Primates Saimiri animal breeding animal care animal tissue biomedical facility disease /disorder model simian AIDSs

项目摘要

The Primate Core at the New England Regional Primate Research Center will be used to test specific hypotheses that arise from basic research or clinical activities of the University of Massachusetts Medical Center CFAR. The Primate Core will translate basic research of clinical observations into specific hypothesis-driven experiments using SIV or SHIV in rhesus monkeys. The New England Regional Primate Research Center maintains approximately 1300 non-human primates and is capable of housing over 100 SIV-or SHIV-infected rhesus monkeys in a specially designed biocontainment facility. The New England Regional Primate Research Center is extensively supported by NIH-funded research programs from the National Center for Research Resources and from the categorical Institutes. The Primate Core will be directed by Dr. Ronald Desrosiers, who has extensive experience in the design and execution of AIDS research projects utilizing non-human primates. The Primate Core will provide partial support for an animal care technician and laboratory technician. A variety of assays will be performed under the Primate Core using samples derived from experimentally-infect animals. The Primates Core will also provides serum, tissue, virus and clone reagents to CFAR investigators. Joint conferences, which already have been taking place, will foster continued interactions, collaborations, and exchanges.

新英格兰地区灵长类动物研究中心的灵长类动物核心将用于检验由基础研究或马萨诸塞大学医学中心的临床活动 CFAR。灵长类动物核心将翻译临床基础研究使用SIV或SHIV观察到特定假设驱动的实验在恒河猴中。新英格兰地区灵长类动物研究中心维护大约1300个非人类灵长类动物，并且能够住房在专门设计的生物疗养设施。新英格兰地区灵长类动物研究中心 NIH资金资助的研究计划得到了国家的广泛支持研究资源中心和分类机构。这灵长类动物核心将由Ronald Desrosiers博士执导，他有广泛的利用艾滋病研究项目的设计和执行经验非人类灵长类动物。灵长类动物核心将为动物护理技术员和实验室技术员。各种各样的测定使用从灵长类动物核心下进行的样品实验感染的动物。灵长类动物核心还将提供血清， CFAR研究人员的组织，病毒和克隆试剂。联合会议，已经发生了，将促进持续的互动，协作和交流。