Conference On Aminoacyl tRNA Synthetases

氨酰 tRNA 合成酶会议

• 批准号: 6365865
• 负责人: CHRISTOPHER S FRANCKLYN
• 金额: $ 0.2万
• 依托单位: UNIVERSITY OF VERMONT & ST AGRIC COLLEGE
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-01 至 2002-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6365865
• 关键词: aminoacid tRNA ligase; biochemical evolution; meeting /conference /symposium; travel

DESCRIPTION (provided by applicant) Aminoacyl-tRNA synthetases are key enzymes in protein synthesis and act as interpreters of the genetic code by relating amino acids to specific tri-nucleotides through aminoacylation of their cognate tRNAs. As such, their structure/function relationships provide important insights into early systems of the decoding machinery. This application describes a proposed workshop, entitled "Aminoacyl-tRNA Synthetases in Biology, Medicine, and Evolution," to be held at the Asilomar Conference, California, from September 23-28, 2001. Owing to the rapid pace of progress and interdisciplinary nature of the synthetase field, organization of this workshop is necessary. The format of the meeting will follow a Gordon Research Conference schedule, with a total of nine formal scientific sessions held in the mornings and evenings. Poster sessions and informal scientific discussions will take place in the afternoons. In each session, major talks of approximately 30 minutes duration will be given by senior investigators, and two to three additional short talks will also be presented by speakers selected on the basis of submitted abstracts. The nine sessions will focus on core issues of tRNA synthetase structure and function, as well as on additional topics of emerging interests. These include the mechanisms of specificity and editing, recognition of tRNA and tRNA-like molecules, alternative functions of synthetases, and artificial aminoacylation systems. This Asilomar meeting represents a unique opportunity to bring together both senior investigators in the field and younger scientists who are still establishing their careers. Participants will be chosen from a highly interactive group of scientists from a variety of disciplines, including representatives from the United States, Europe, and Japan. This is the fourth such meeting to be held in the last decade, with previous meetings held in Autrans, France (1990), Taos, New Mexico (1997), Mittelwihr, France (1998).

描述（由申请人提供）氨基酰基-TRNA合成酶是关键酶 在蛋白质合成中，通过关联 通过氨基酸通过其同源的氨基酸到特定的三核苷酸 trnas。因此，他们的结构/功能关系提供了重要的 洞悉解码机械的早期系统。此应用程序 描述了一个拟议的研讨会，名为“生物学中的氨基酰基-TRNA合成酶， 医学和进化 从2001年9月23日至28日开始。由于进步的迅速和 合成酶领域的跨学科性质，该研讨会的组织 是必要的。会议的格式将遵循戈登研究 会议时间表，共有9次正式的科学会议 早晨和夜晚。海报会议和非正式科学讨论 将在下午举行。在每个会议中，关于 高级调查员将提供约30分钟的时间，并将 选定的演讲者还将提出另外两到三场简短的谈话 根据提交的摘要。九个会议将重点放在核心上 tRNA合成酶结构和功能以及其他问题 新兴兴趣的话题。这些包括特异性机制和 编辑，识别tRNA和tRNA样分子，替代功能 合成酶和人工氨基化系统。这次Asilomar会议 代表了将两个高级调查员聚集在一起的独特机会 仍在建立职业生涯的领域和年轻科学家。 参与者将从高度互动的科学家组中选择 各种学科，包括来自美国的代表 欧洲和日本。这是在上次举行的第四届此类会议 十年，以前在法国Autrans举行的会议（1990年），新墨西哥州陶斯 （1997），法国米特维赫（Mittelwihr）（1998）。