BOUN HOONG SOUTHAVONG LAO MEDICINAL PLANTS--POTENTIAL SOURCE OF NEW MEDICINES

BOUN HOONG SOUTHAVONG 老挝药用植物——新药的潜在来源

• 批准号: 6504592
• 负责人: DJAJA D SOEJARTO
• 金额: $ 13.47万
• 依托单位: UNIVERSITY OF ILLINOIS AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-30 至 2002-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6504592
• 关键词: antimalarial agents; antiviral agents; bioassay; central nervous system disorders; community; computer system design /evaluation; cooperative study; data collection; ethnic group; folk medicine; health care; health education; human subject; information retrieval; information systems; international cooperation; interview; medicinal plants; plant extracts; southeast Asia

Associate Program 2 will be performed by the Research Institute of Medicinal Plants (RIMP), Vientiane, Laos. RIMP maintains a network of Traditional Medicine stations in different areas of Laos, through which it will conduct field interviews among the different ethnic groups in Laos regarding use of medicinal plants. Those with uses for Malaria, viral diseases and CNS-related symptoms will be emphasized. Plants with these uses will be collected in bulk samples and extracted at the Phytochemistry Laboratory in RIMP; those with uses against viral disease and malaria will be sent to AP-3 (Program for Collaborative Research in the Pharmaceutical Sciences, University of Illinois at Chicago), while those with uses against CNS-related symptoms will be sent to AP-5 (Glaxo Wellcome Research and Development). Voucher herbarium specimens of all medicinal plants will be collected as far as possible, and systematic data taken on their collection and use. Plant species identifications and medicinal uses of plants will be entered into the NAPIS data management system to assemble a database of plant uses which will act as a basis for further study of the medicinal plants of Laos. Identified species will be analyzed using printouts from the NAPRALERT database and other literature to evaluate potential toxicity and efficacy. Results of this analysis will be communicated to the scientific community through publications. Conservation status of Laos medicinal plants will be examined so that appropriate recommendations for protection of various species may be made to the Lao PDR Government. Community health promotion and promotion of children's education will be the major efforts of reciprocity for communities that collaborate with RIMP investigators; support of the network of Traditional Medicine Stations will also be part of reciprocity, as these Stations assist RIMP in maintaining contact with ethnic communities, as well as serving the health needs of those communities. Finally, human resources and infrastructure upgrading at RIMP will take place, including international training in ethnobotanical research, phytochemistry, and conservation biology.

副计划2将由研究院执行 药用植物 (RIMP)，老挝万象。 RIMP 维护着一个网络 老挝不同地区的传统医学站，通过这些站 将对老挝各民族进行实地采访 关于药用植物的使用。那些用于疟疾、病毒的 将强调疾病和中枢神经系统相关症状。含有这些的植物 用途将收集成批量样品并在植物化学中提取 RIMP实验室；那些用于对抗病毒性疾病和疟疾的药物将 被发送到 AP-3（制药合作研究计划） 科学，伊利诺伊大学芝加哥分校），而那些有用途的 针对中枢神经系统相关症状的信息将被发送至 AP-5（葛兰素威康研究 和发展）。所有药用植物的凭证植物标本馆标本将 尽可能收集并系统地获取其数据 收集和使用。植物种类鉴定及药用用途 工厂将进入NAPIS数据管理系统进行组装 植物用途数据库，将作为进一步研究的基础 老挝的药用植物。将使用以下方法分析已识别的物种 NAPRALERT 数据库和其他文献的打印输出以进行评估 潜在的毒性和功效。该分析的结果将是 通过出版物向科学界传达。 将检查老挝药用植物的保护状况，以便 可以提出保护各种物种的适当建议 老挝人民民主共和国政府。社区健康促进和促进 孩子的教育将是互惠的主要努力 与 RIMP 调查人员合作的社区；支持的 传统医药站网络也将成为互惠的一部分， 因为这些站协助 RIMP 与少数民族保持联系 社区，以及满足这些社区的健康需求。 最后，RIMP 的人力资源和基础设施升级将需要 地点，包括民族植物学研究的国际培训， 植物化学和保护生物学。