BOUN HOONG SOUTHAVONG LAO MEDICINAL PLANTS--POTENTIAL SOURCE OF NEW MEDICINES

BOUN HOONG SOUTHAVONG 老挝药用植物——新药的潜在来源

• 批准号: 6359029
• 负责人: DJAJA D SOEJARTO
• 金额: $ 7.8万
• 依托单位: UNIVERSITY OF ILLINOIS AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-09-30 至 2001-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6359029
• 关键词: antimalarial agents; antiviral agents; bioassay; central nervous system disorders; community; computer system design /evaluation; cooperative study; data collection; ethnic group; folk medicine; health care; health education; human subject; information retrieval; information systems; international cooperation; interview; medicinal plants; plant extracts; southeast Asia

Associate Program 2 will be performed by the Research Institute of Medicinal Plants (RIMP), Vientiane, Laos. RIMP maintains a network of Traditional Medicine stations in different areas of Laos, through which it will conduct field interviews among the different ethnic groups in Laos regarding use of medicinal plants. Those with uses for Malaria, viral diseases and CNS-related symptoms will be emphasized. Plants with these uses will be collected in bulk samples and extracted at the Phytochemistry Laboratory in RIMP; those with uses against viral disease and malaria will be sent to AP-3 (Program for Collaborative Research in the Pharmaceutical Sciences, University of Illinois at Chicago), while those with uses against CNS-related symptoms will be sent to AP-5 (Glaxo Wellcome Research and Development). Voucher herbarium specimens of all medicinal plants will be collected as far as possible, and systematic data taken on their collection and use. Plant species identifications and medicinal uses of plants will be entered into the NAPIS data management system to assemble a database of plant uses which will act as a basis for further study of the medicinal plants of Laos. Identified species will be analyzed using printouts from the NAPRALERT database and other literature to evaluate potential toxicity and efficacy. Results of this analysis will be communicated to the scientific community through publications. Conservation status of Laos medicinal plants will be examined so that appropriate recommendations for protection of various species may be made to the Lao PDR Government. Community health promotion and promotion of children's education will be the major efforts of reciprocity for communities that collaborate with RIMP investigators; support of the network of Traditional Medicine Stations will also be part of reciprocity, as these Stations assist RIMP in maintaining contact with ethnic communities, as well as serving the health needs of those communities. Finally, human resources and infrastructure upgrading at RIMP will take place, including international training in ethnobotanical research, phytochemistry, and conservation biology.

副计划2将由研究所进行 老挝万象植物（RIMP）。 RIMP保持一个网络 老挝不同地区的传统医学站 将在老挝不同种族中进行现场访谈 关于使用药用植物。那些有疟疾，病毒的人 将强调疾病和与中枢神经系统有关的症状。这些植物 用途将在批量样品中收集，并在植物化学上提取 RIMP实验室；那些使用病毒疾病和疟疾使用的人会 被发送到AP-3（制药的合作研究计划 科学，伊利诺伊大学芝加哥大学），而那些 针对与CNS相关症状的症状将发送至AP-5（Glaxo Wellcome研究 和发展）。所有药用植物的代金券标本室标本将 尽可能收集到他们的系统数据 收集和使用。植物物种的鉴定和药用 植物将被输入NAPIS数据管理系统以组装 植物用途的数据库，该数据库将作为进一步研究的基础 老挝的药用植物。确定的物种将使用 来自Napralert数据库和其他文献的打印输出来评估 潜在的毒性和功效。该分析的结果将是 通过出版物与科学界传达。 将检查老挝药用植物的保护状况，以便 可以提出适当的保护各种物种的建议 去老挝政府。社区健康促进和促进 儿童教育将是互惠的主要努力 与RIMP调查人员合作的社区；支持 传统医学站的网络也将成为互惠的一部分， 由于这些电台协助RIMP保持与种族的联系 社区，以及为这些社区的健康需求服务。 最后，RIMP升级的人力资源和基础设施将进行 地点，包括国际植物学研究的国际培训， 植物化学和保护生物学。