HEARING & SPEECH OF YOUNG MALES WITH FRAGILE X SYNDROME

听力

• 批准号: 6333966
• 负责人: Joanne E. Roberts
• 金额: $ 7.27万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-05-01 至 2003-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6333966
• 关键词: audiometry; audiotape; behavioral /social science research tag; computer data analysis; developmental neurobiology; electroencephalography; electrophysiology; fragile X syndromes; hearing disorders; human subject; longitudinal human study; male; medical complication; middle childhood (6-11); neural information processing; patient oriented research; phonology; sound perception; speech disorders; speech recognition; vocalization

DESCRIPTION: (Adapted from the applicant's Description) This project proposes to conduct two pilot studies on the hearing and speech intelligibility skills of young males with fragile X syndrome. The specific objectives are to determine if atypical peripheral hearing, auditory brainstem responses, and higher auditory processing skills are displayed in males with fragile X syndrome, and to determine the phonologic, prosodic, segmental, and oral-motor factors that affect the speech intelligibility of young males with fragile X syndrome. In Study 1, the investigators hypothesize that males with fragile X syndrome, compared to typically developing controls, will display normal peripheral and brainstem measures of hearing, and will show poorer higher auditory processing for recognizing speech in noise than in quiet. In Study II, the investigators hypothesize that males with fragile X syndrome will show poorer speech intelligibility in conversational speech due to phonological errors, prosodic features, segmental features, and oral-motor skills.

描述：（根据申请人的描述进行了改编）此项目 建议对听证和言语进行两项试点研究 患有脆弱X综合征的年轻男性的清晰度技能。 具体 目标是确定非典型外围听力，听觉脑干是否 响应和更高的听觉处理技巧在男性中显示 脆弱的X综合征，并确定语音，韵律，分段和 影响年轻男性语音清晰度的口服运动因素与 脆弱的X综合征。 在研究1中，研究人员假设男性 与通常开发控件相比，脆弱的X综合征将显示 正常的外围和脑干听力指标，并将显示较差 识别噪音中语音的听觉处理要比安静更高。 在 研究II，研究人员假设患有脆弱X综合征的雄性 在会话演讲中，将显示出较差的语音清晰度 语音错误，韵律特征，节段特征和口服运动 技能。