TESTING INTERVENTIONS IN PEDIATRIC ASTHMA

测试小儿哮喘的干预措施

• 批准号: 6228467
• 负责人: ELIZABETH L MCQUAID
• 金额: $ 7.7万
• 依托单位: RHODE ISLAND HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-05-15 至 2003-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6228467
• 关键词: adolescence (12-20); age difference; asthma; audiotape; behavior therapy; behavioral /social science research tag; education evaluation /planning; health education; human morbidity; human subject; human therapy evaluation; interview; middle childhood (6-11); patient care management; patient oriented research; pediatrics; therapy compliance

DESCRIPTION (Adapted from applicant's description): This project seeks preliminary funding to compare two interventions to increase adherence and reduce morbidity for children with persistent asthma. Recent studies demonstrate that children with asthma typically take less than half of their prescribed doses of preventive medications. Targeting this problem specifically has the potential to improve symptoms, decrease morbidity, and decrease health care utilization in pediatric asthma. Focus groups will first be conducted to provide feedback regarding preliminary intervention materials. Then, 110 families with a child with persistent asthma (between 8-14) will be recruited into a month's baseline, including electronic adherence assessment, and evaluation of asthma know1edge, self-efficacy, and morbidity. At the end of baseline, families whose children exhibit less than 70% adherence (expected n equals 60) will be randomized to one of two treatment conditions, either Behavioral Feedback (BF) or Asthma Education (AE). Each treatment consists of three individualized one-hour sessions over a month's time. The BF condition includes feedback regarding medication use, problem-solving regarding adherence barriers, and behavioral contracting. The AE condition provides education regarding asthma biology and medications, environmental control, and symptom assessment and management. Adherence and asthma morbidity will be assessed during the intervention month, and one month post-treatment. It is expected that: 1) Participants in the EF condition will demonstrate greater increases in adherence than participants in the AE condition and 2) Participants in the BF condition will have decreased functional morbidity due to asthma relative to participants receiving AE. Preliminary analyses will determine relevant covariates; key analyses will determine intervention effects within and across groups. Exploratory analyses will investigate mediators of behavior change. Results will be used to design a larger, randomized controlled trial comparing behavioral feedback to asthma education.

描述（改编自申请人的描述）：该项目寻求 初步资助用于比较两种干预措施以提高依从性和 降低持续性哮喘儿童的发病率。最近的研究 证明患有哮喘的儿童通常只服用不到一半的药物 规定剂量的预防药物。针对这个问题 特别具有改善症状、降低发病率的潜力，并且 减少小儿哮喘的医疗保健利用率。 首先将进行焦点小组讨论，以提供初步反馈 干预材料。然后，110个有持续性哮喘孩子的家庭 （8-14之间）将被招募到一个月的基线，包括电子 依从性评估以及哮喘知识、自我效能和哮喘知识的评估 发病率。 在基线结束时，孩子表现低于 70% 的依从性（预期 n 等于 60）将被随机分配到以下两个之一 治疗条件，行为反馈 (BF) 或哮喘教育 （AE）。 每次治疗包括三个个性化的一小时疗程，持续时间 一个月的时间。 BF 状况包括有关药物使用的反馈， 解决有关遵守障碍和行为契约的问题。 AE 状况提供有关哮喘生物学和药物的教育， 环境控制、症状评估和管理。依从性和 将在干预月份和一个月内评估哮喘发病率 治疗后。预计： 1) EF 条件的参与者将 与 AE 参与者相比，表现出更大的依从性 条件和2）BF条件下的参与者将会减少 与接受 AE 的参与者相比，哮喘导致的功能发病率。 初步分析将确定相关协变量；关键分析将 确定组内和组间的干预效果。 探索性分析 将调查行为改变的中介因素。 结果将用于设计 比较行为反馈与哮喘的大型随机对照试验 教育。