Asthma Management and Ethnic Disparities at the Adolescent Transition

青少年过渡时期的哮喘管理和种族差异

基本信息

批准号：
8080272
负责人：
ELIZABETH L MCQUAID
金额：
$ 11.31万
依托单位：
RHODE ISLAND HOSPITAL
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
起止时间：
2009-06-15 至 2014-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8080272
关键词：
Acculturation Address Adherence Adolescence Adolescent Affect African American Area Asthma Behavior Behavior Therapy Behavioral Genetics Belief Child Childhood Childhood Asthma Chronic Disease Clinical Complex Data Data Analyses Data Set Development Disease Disease Management Enrollment Epidemiology Ethics Ethnic Origin Ethnic group Evaluation Faculty Family Fellowship Program Funding Future Goals Grant Health Services Accessibility Health education Healthcare Human Immigrant Intervention Interview K-Series Research Career Programs Latino Longitudinal Studies Mediating Mentors Mentorship Minority Minority Groups Monitor Morbidity - disease rate Parents Pattern Pharmaceutical Preparations Play Postdoctoral Fellow Process Protocols documentation Psychiatry Public Health Puerto Rico Randomized Controlled Trials Recording of previous events Recruitment Activity Regimen Relative (related person)Research Research Design Research Infrastructure Research Project Grants Resources Role Sampling Supervision Testing Time Training Universities Work Youth disorder control eighth grade follow-up health disparity high school improved individual responsibility interest medical schools medication compliance mortality patient oriented research professor programs prospective public health relevance skills statistics tenth grade therapy development

项目摘要

DESCRIPTION (provided by applicant): This revised K24 application proposes a mentorship program in patient-oriented research in pediatric asthma, with a specific focus on health care disparities and disease management behaviors. The K24 Candidate is an Associate Professor (Research) in the Department of Psychiatry and Human Behavior of the Warren Alpert Medical School at Brown University, with a history of funding in behavioral interventions to improve disease management and address health disparities in pediatric asthma. Training Plan: The candidate will obtain additional training in longitudinal data analysis, behavioral genetics, evaluation and assessment in health education, and health care access for Latino immigrants to enrich her skills and mentoring capacity in future health care disparities research. Research Plan: A longitudinal study of medication adherence for Latinos and non-Latino white (NLW) youth with asthma is proposed to assess the differential course of medication adherence by culture across the transition to adolescence. Three waves of 50 youth with persistent asthma (150 total, 25 Latino, 25 NLW in each wave) will complete a multimethod assessment of asthma status, family factors, medication beliefs, and controller medication use. Assessments will occur in eighth grade, then again in tenth grade, with continuous monitoring of medication adherence throughout. Analyses will evaluate the role of medication beliefs and family connectedness in supporting asthma management in Latino and NLW youth with persistent asthma, and assess differential trajectories of medication use by ethnic group over time. Mentoring Plan: The proposed mentoring plan offers participation in an RCT to address asthma disparities in medication use, access to an ongoing educational program for asthma that serves over 700 families a year, and an archival dataset that includes a wealth of data on disease management behavior in over 800 Latino and NLW children in Rl and Puerto Rico. An additional ongoing seminar is planned for junior faculty on topics such as recruiting and retaining culturally diverse samples, and preparing research grant applications. This overall plan capitalizes on the rich resources and training opportunities available to postdoctoral fellows and junior faculty at Brown, including seven T32 fellowship programs, numerous junior faculty with K awards and small grants, seminars in research design, ethics, and statistics, and established infrastructure for evaluation. PUBLIC HEALTH RELEVANCE: Public Health Significance: Asthma is a common chronic illness in which minority children are disproportionately affected. Facilitating mentorship and execution of high quality patient-oriented research in this area is critical to address health care disparities. PROJECT/

描述（由申请人提供）：这份修订后的 K24 申请提出了一项以患者为导向的小儿哮喘研究的指导计划，特别关注医疗保健差异和疾病管理行为。 K24 候选人是布朗大学沃伦阿尔珀特医学院精神病学和人类行为系的副教授（研究），拥有资助行为干预的历史，以改善疾病管理和解决小儿哮喘的健康差异。培训计划：候选人将获得纵向数据分析、行为遗传学、健康教育评估和评估以及拉丁裔移民医疗保健获取方面的额外培训，以丰富她在未来医疗保健差异研究中的技能和指导能力。研究计划：建议对患有哮喘的拉丁裔和非拉丁裔白人 (NLW) 青少年的药物依从性进行纵向研究，以评估从文化到青春期过渡期间药物依从性的差异过程。三批 50 名患有持续性哮喘的青少年（每批总共 150 名，25 名拉丁裔，25 名 NLW）将完成对哮喘状况、家庭因素、药物信念和控制药物使用的多方法评估。评估将在八年级进行，然后在十年级再次进行，并在整个过程中持续监测药物依从性。分析将评估药物信念和家庭联系在支持患有持续性哮喘的拉丁裔和非白人青少年的哮喘管理中的作用，并评估不同种族群体随时间推移的不同药物使用轨迹。指导计划：拟议的指导计划提供参与随机对照试验（RCT）以解决哮喘药物使用差异的机会，参与每年为 700 多个家庭提供服务的持续哮喘教育计划，以及包含有关疾病管理行为的大量数据的档案数据集罗德岛州和波多黎各的 800 多名拉丁裔和非白人儿童中。计划为初级教师举办一场额外的研讨会，主题包括招募和保留文化多样性样本以及准备研究资助申请等。该总体计划利用了布朗大学为博士后研究员和初级教师提供的丰富资源和培训机会，包括七个 T32 奖学金项目、众多获得 K 奖和小额赠款的初级教师、研究设计、伦理和统计学方面的研讨会以及已建立的基础设施进行评估。公共卫生相关性：公共卫生意义：哮喘是一种常见的慢性疾病，少数族裔儿童受到的影响尤为严重。促进该领域高质量的以患者为导向的研究的指导和执行对于解决医疗保健差异至关重要。项目/