AN INTERVENTION FOR MALE STD PATIENTS IN INDIA
印度男性性病患者的干预措施
基本信息
- 批准号:6373977
- 负责人:
- 金额:$ 57.85万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2000
- 资助国家:美国
- 起止时间:2000-08-15 至 2004-07-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
India now has the greatest number of HIV infections of any country in the world, with heterosexual transmission responsible for 75% of its reported HIV cases. In Mumbai, formerly Bombay, the prevalence of HIV among sex workers (CSWs) is 60-80%. Interventions targeting CSWs have met with limited success given these women's lack of power to negotiate condom use; concomittantly, HIV infection among male sexually transmitted disease (STD) patients, a majority of whom are regular clients Of CSWs, has risen to 36%. Targeting male STD patients can be an effective HIV prevention strategy, as these men represent a critical link in the transmission Of HW to the general population. The high prevalence of STDs, particularly genital ulcers, as well as lack of adequate diagnosis and timely treatment, also contribute to increased HIV transmission in this group. We have conducted a pilot study among male STD patients in a public clinic in Mumbai that has provided baseline information on sexual risk behavior and the feasibility of performing a behavioral intervention. We base our current proposal on this extensive pilot data. The goals of this proposal are to perform a randomized, controlled trial of a behavioral intervention when added to standard care (STD treatment, with HIV testing and counseling) compared with standard care alone, among male STD patients in two public clinics in Mumbai. We will determine the impact of the intervention using biological outcome measures, specifically, HIV incidence over a one-year follow-up period. We will also measure the program's effect on self-reported risk behaviors, including condom use, visits to sex workers, number of sexual partners and health seeking behavior. We will determine the incidence and prevalence of bacterial and viral STDs using nucleic acid amplification techniques to identify the etiology of genital ulcer disease, urethritis, and asymptomatic infections. There have been no controlled trials of behavioral interventions in India targeting male clients of sex workers or STD patients. There is an urgent need to test strategies that are feasible, effective, sustainable and applicable to similar settings in India and elsewhere in Asia. This study will provide valuable information on the added efficacy of a behavioral approach to HIV control.
印度现在拥有世界上任何国家的艾滋病毒感染数量最多,异性恋传播造成了其报告的艾滋病毒案例的75%。在孟买(以前是孟买),性工作者(CSW)中艾滋病毒的患病率为60-80%。鉴于这些妇女缺乏谈判使用安全套的能力,针对CSW的干预措施取得了有限的成功;同时,男性性传播疾病(STD)患者中的艾滋病毒感染(其中大多数是CSW的常规客户)上升至36%。靶向男性性病患者可以是一种有效的艾滋病毒预防策略,因为这些男性代表了HW传播到普通人群的关键联系。性病,特别是生殖器溃疡的高患病率,以及缺乏足够的诊断和及时治疗,也有助于该组的HIV传播增加。我们在孟买的一家公共诊所中对男性性病患者进行了一项试点研究,该研究提供了有关性风险行为的基线信息以及进行行为干预的可行性。我们将当前的建议基于此广泛的试点数据。该提案的目标是在孟买的两家公共诊所中的男性性病患者中,与单独的标准护理相比,与单独的标准护理相比,将行为干预的随机,对照试验(性病治疗,艾滋病毒测试和咨询)进行。我们将使用生物学结局指标(特别是在一年的随访期间)确定干预措施的影响。我们还将衡量该计划对自我报告的风险行为的影响,包括使用避孕套,对性工作者的访问,性伴侣的数量和寻求健康的行为。我们将使用核酸扩增技术来确定细菌和病毒性病的发生率和患病率,以鉴定生殖器溃疡疾病,尿道炎和无症状感染的病因。印度没有针对性工作者或性病患者的男性客户的行为干预措施的对照试验。迫切需要测试可行,有效,可持续性且适用于印度和亚洲其他地方的类似环境的策略。这项研究将提供有关行为方法控制艾滋病毒控制的额外功效的宝贵信息。
项目成果
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CHRISTINA P LINDAN其他文献
CHRISTINA P LINDAN的其他文献
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{{ truncateString('CHRISTINA P LINDAN', 18)}}的其他基金
International Traineeships in AIDS Prevention Studies (ITAPS)
艾滋病预防研究国际培训(ITAPS)
- 批准号:
10013921 - 财政年份:2020
- 资助金额:
$ 57.85万 - 项目类别:
International Traineeships in AIDS Prevention Studies (ITAPS)
艾滋病预防研究国际培训(ITAPS)
- 批准号:
10181081 - 财政年份:2020
- 资助金额:
$ 57.85万 - 项目类别:
International Traineeships in AIDS Prevention Studies (ITAPS)
艾滋病预防研究国际培训(ITAPS)
- 批准号:
10597008 - 财政年份:2020
- 资助金额:
$ 57.85万 - 项目类别:
International Traineeships in AIDS Prevention Studies (ITAPS)
艾滋病预防研究国际培训(ITAPS)
- 批准号:
10386931 - 财政年份:2020
- 资助金额:
$ 57.85万 - 项目类别:
On the road to recovery: building Liberia's clinical and epidemiological research capacity to respond to emerging infectious diseases
走上复苏之路:建设利比里亚应对新发传染病的临床和流行病学研究能力
- 批准号:
9438657 - 财政年份:2017
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$ 57.85万 - 项目类别:
An Intervention for Male STD Patients in India
针对印度男性性病患者的干预措施
- 批准号:
7085430 - 财政年份:2000
- 资助金额:
$ 57.85万 - 项目类别:
An Intervention for Male STD Patients in India
针对印度男性性病患者的干预措施
- 批准号:
6841547 - 财政年份:2000
- 资助金额:
$ 57.85万 - 项目类别:
An Intervention for Male STD Patients in India
针对印度男性性病患者的干预措施
- 批准号:
6917025 - 财政年份:2000
- 资助金额:
$ 57.85万 - 项目类别:
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