DENTAL COMPOSITES BASED ON RIGID, HYPERBRANCHED POLYMERS

基于刚性、超支化聚合物的牙科复合材料

基本信息

批准号：
6175921
负责人：
SCOTT R SCHRICKER
金额：
$ 3.7万
依托单位：
OHIO STATE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
1999
资助国家：
美国
起止时间：
1999-08-01 至 2002-07-31
项目状态：
已结题

项目摘要

DESCRIPTION: (Adapted from applicant's abstract) Dental composite restoratives have found wide use as an aesthetic substitute for dental amalgams. However, there is need to improve the durability and longevity of these materials. Because the final restorative must have handling properties that are acceptable to the dentist, any method used to improve the properties of the restorative must not significantly increase the viscosity. The addition of linear polymers to dental composites increases the physical properties of restoratives; however, a concomitant increase in viscosity is often observed which impedes the clinical application of these materials. However, hyperbranched polymers, a new class of high-branched polymeric materials, maintain relatively low solution or melt viscosities that do not increase significantly with increases in molecular weight. This proposal will establish the ability of methacrylated commercial hyperbranced polymers to improve the properties of dental restoratives while maintaining a low, functional viscosity. Following these preliminary studies, high performance hyperbranced polymers, rigidified though intramolecular hydrogen bonding, will be synthesized to further enhance the properties of the restoratives. These modified hyperbranced polymers will be formulated with BisGMA-TEGDMA and the physical properties will be evaluated using standard techniques. It is anticipated that the hyperbranced modified BisGMA-TEGDMA will demonstrate the improved properties that can be expected from high molecular weight polymers but these materials will not experience any significant increase in viscosity.

描述：（改编自申请人的摘要）牙科复合修复剂已广泛用作牙科汞合金的美学替代品。然而，需要提高这些材料的耐用性和寿命。因为最终的修复体必须具有可接受的处理性能对于牙医来说，任何用于改善修复体性能的方法不得显着增加粘度。添加线性聚合物牙科复合材料可提高修复材料的物理性能；然而，经常观察到粘度随之增加，这阻碍了这些材料的临床应用。然而，超支化聚合物新型高支化高分子材料，保持相对较低水平溶液或熔体粘度不会随着增加而显着增加在分子量上。该提案将建立甲基丙烯酸酯的能力商用超支化聚合物可改善牙科性能修复剂，同时保持低功能粘度。遵循这些初步研究，高性能超支化聚合物，尽管已硬化分子内氢键，将被合成以进一步增强修复剂的特性。这些改性超支化聚合物将采用 BisGMA-TEGDMA 配制，并评估物理性能使用标准技术。预计超支化修饰 BisGMA-TEGDMA 将展示预期的改进性能来自高分子量聚合物，但这些材料不会经历任何粘度显着增加。