RENOV ANIMAL FACIL: DIABETES

RENOV 动物设施：糖尿病

• 批准号: 6794424
• 负责人: JOAN F. LORDEN
• 金额: $ 30万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-05-01 至 2003-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6794424
• 关键词: Primates; Rodentias; animal colony; biomedical facility; building /facility design /renovation; diabetes mellitus; disease /disorder; dogs; imaging /visualization /scanning; surgery; university

DESCRIPTION (provided by applicant): This application requests matching funds for Phase II of the renovation of the VH Animal Facility at the UAB. VH was completed in 1971, and remains the largest research building at UAB. The 35,438 sq. ft. assigned to the Animal Resources Program in the basement of VH is the largest of the UAB animal facilities. It currently houses over 15,000 animals, and provides housing and support services for 30 percent of the animal population at UAB, representing 14 species including rodents, dogs, farm animals, and non-human primates (NHP). This application proposes to renovate and expand animal research support space for surgery and imaging large and small animal species. It also proposes to consolidate central support service space. It will replace one of four air handlers that serve this facility, relocate the cage wash system, and improve adjacencies of many support areas near the loading dock, lead to improved traffic flow, improve security, ventilation, and plumbing, and abate asbestos. UAB is committed to the prevention and treatment of diseases as prioritized in the "Healthy People 2010" directive. The investigators at UAB that will directly benefit from this application have diverse research interests that include heart disease, cancer, diabetes, gene therapy, chemoprevention, vaccine development and delivery, neural processing of visual stimulus and memory, and the mechanisms responsible for immune responses. The proposed renovations will thus provide state-of-the-art animal facilities to support federally-funded research in areas emerging as high priorities for new therapeutic strategies and health maintenance.

描述（由申请人提供）：本申请要求对UAB的VH动物设施进行翻新的II阶段匹配。 VH于1971年完成，仍然是UAB最大的研究大楼。在VH地下室分配给动物资源计划的35,438平方英尺是UAB动物设施中最大的。它目前容纳15,000多只动物，并为UAB的30％的动物人群提供住房和支持服务，代表14种物种，包括啮齿动物，狗，农场动物和非人类灵长类动物（NHP）。该应用建议翻新和扩大动物研究支持手术和成像大小动物物种的空间。它还建议巩固中央支持服务领域。它将取代为该设施提供服务，重新安置笼子清洗系统的四个空气处理程序之一，并改善装载码头附近的许多支撑区域的邻接，从而改善交通流量，改善安全性，改善安全性，通风和管道，并减轻石棉。 UAB致力于预防和治疗“健康人2010”指令中的优先级。 UAB的研究人员将直接从该应用中受益，具有多种研究兴趣，包括心脏病，癌症，糖尿病，基因治疗，化学预防，疫苗开发和输送，视觉刺激和记忆的神经加工以及负责免疫反应的机制。因此，拟议的翻新将提供最先进的动物设施，以支持在新出现的新治疗策略和健康维护方面出现的联邦资助研究。