TESLA ADDITION TO CTR FOR MR RES: BRAIN, COGNITIVE PRIMATE MODEL, COCAINE: AIDS

特斯拉在 MR RES 的 CTR 中添加了内容：大脑、认知灵长类动物模型、可卡因：艾滋病

• 批准号: 6794517
• 负责人: ALFRED F MICHAEL
• 金额: $ 76.71万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-15 至 2003-09-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6794517
• 关键词: AIDS; Primates; bioimaging /biomedical imaging; biological models; biomedical facility; brain; building /facility design /renovation; clinical research; cocaine; imaging /visualization /scanning; magnetic resonance imaging; nuclear magnetic resonance spectroscopy

DESCRIPTION (provided by applicant): The CMRR is an interdepartmental and interdisciplinary research laboratory which provides unique instrumentation, expertise and infrastructure to enable the faculty, trainees and staff of several institutions to carry out biomedical research that utilizes the unique capabilities provided by high field MRI and MRS methodology. In this capacity, as well as being a National Biotechnology Research Resource, CMRR services a very large community of National Institutes of Health (NIH)-funded researchers working in MR physics for biomedical applications, neurosciences, functional brain mapping, brain metabolism, metabolic disorders, and cardiac pathology and bioenergetics. The specific aim of this application is the construction of a new, approximately 2,700 sq. ft. addition to the existing CMRR building. The new addition is for the purpose of establishing a Core Laboratory centered on a new, state-of-the-art ultrahigh field 9.4 Tesla (T) MRI and MRS instrument with a large enough bore size (65 cm clear bore) to perform human and non-human primate (NHP) studies. Currently, space within the CMRR to house this instrument does not exist. Supported by the Wisconsin Regional Primate Research Center (WRPRC), and full animal facilities located within the CMRR for animal model studies, as well as the UM General Clinical Research Center (GCRC) for human studies, the proposed addition will represent a major enhancement for interdisciplinary and collaborative research that rely on high field magnetic resonance techniques. The total cost of the proposed addition is projected at $1.5 million. The UM will provide the required 50 percent matching funds.

描述（由申请人提供）：CMRR是一个跨部门和跨学科研究实验室，提供独特的仪器，专业知识和基础设施，以使几个机构的教职员工，受训人员和员工能够进行生物医学研究，以利用高领域MRI和MRS方法论提供的独特功能。 CMRR以这种能力以及作为国家生物技术研究资源，服务于国家卫生研究院（NIH）资助的非常大的社区，从事生物医学应用，神经科学，功能性脑图，大脑代谢，代谢性疾病，代谢性病理学以及心态病理学以及生物病理学和生物味学的研究人员。该应用程序的具体目的是建造新的，大约2,700平方英尺的现有CMRR建筑物。新增的目的是建立一个以新的，最先进的超高领域为中心的核心实验室9.4 Tesla（T）MRI和MRS MRI和MRS仪器，并具有足够大的孔径（65厘米透明孔）进行人类和非人类灵长类动物（NHP）研究。当前，CMRR内部容纳该乐器的空间不存在。在威斯康星州地区灵长类动物研究中心（WRPRC）以及位于CMRR内的全动物设施以及人类研究中的UM通用临床研究中心（GCRC）的支持下，拟议中的添加将代表依靠高现场磁性谐振技术的跨学科和协作研究的重大增强。拟议中的总成本预计为150万美元。 UM将提供所需的50％匹配资金。