ALCOHOL USE DURING PREGNANCY--A LONGITUDINAL STUDY

怀孕期间饮酒——一项纵向研究

• 批准号: 6362161
• 负责人: NANCY Lee DAY
• 金额: $ 15.93万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 1985
• 资助国家: 美国
• 起止时间: 1985-05-01 至 2003-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6362161
• 关键词: academic achievement; adolescence (12-20); alcoholic beverage consumption; behavior prediction; behavioral /social science research tag; child behavior disorders; child physical development; child psychology; clinical research; developmental neurobiology; disease /disorder onset; embryo /fetus toxicology; fetal alcohol syndrome; human subject; juvenile delinquency; longitudinal human study; neuropsychological tests; neuropsychology; postnatal growth disorder; psychomotor function; substance abuse epidemiology

The Maternal Health Practices and Child Development Project (MHPCD) is a prospective study of the pregnancy outcome of 650 women who were interviewed in their fourth and seventh prenatal months, and with their offspring, at delivery, 8 and 19 months, 3,6, and 10 years. The women represent the spectrum of prenatal alcohol use allowing us to look a the effects of light moderate, and heavier levels of exposure. We have identified significant effects of prenatal alcohol exposure on the development of the central nervous system (CNS) including changes in sleep-EEG, behavior, mood, cognitive, and neuropsychological functioning. Exposed children are smaller through the age of 10 and have a later onset of puberty. At ages 6 and 10, alcohol exposure during gestation predicted poorer academic performance and delinquency, and at age 10, association with substance-using peers. At 14 years, we will monitor the already observed effects of prenatal alcohol exposure on neuropsychological functioning and affect and identify effects that become evident with maturation. In addition , we will assess the effects of prenatal exposure to alcohol on the development and progression of academic problems, delinquency , and substance us and abuse. We will monitor the already observed effects of prenatal alcohol exposure on neuropsychological function and affect and identify latent effects that become evident with maturation. In addition, we will assess the effects of prenatal exposure to alcohol on the development and progression of academic problems, delinquency, and substance use and abuse. We will assess the longitudinal effects of antecedent differences in mental and physical development, temperament, psychological status, activity levels, academic performance, behavior problems, he environment, and prenatal alcohol exposure on the adolescents' alcohol and other drug use.

孕产妇保健实践和儿童发展项目 (MHPCD) 是一项针对 650 名女性妊娠结局的前瞻性研究 在产前第四个月和第七个月接受采访，并 他们的后代，在分娩时、8个月和19个月、3,6岁和10岁时。 这些女性代表了产前饮酒的范围，使我们能够 看看光的效果适中，而重度的水平 接触。 我们已经发现产前酒精的显着影响 接触中枢神经系统（CNS）的发育 包括睡眠脑电图、行为、情绪、认知和认知的变化 神经心理功能。 暴露在外的儿童体型较小 10 岁，青春期开始较晚。 6岁和10岁时， 怀孕期间接触酒精预示着学业成绩较差 表现和犯罪行为，以及在 10 岁时，与 使用物质的同龄人。 14 岁时，我们将监测已观察到的产前影响 酒精暴露对神经心理功能的影响 识别随着成熟而变得明显的影响。 此外 ， 我们将评估产前接触酒精对 学术问题、不良行为的发展和进展，以及 物质和虐待。 我们将监测已经观察到的效果 产前酒精暴露对神经心理功能的影响 影响并识别明显的潜在影响 成熟。 此外，我们将评估产前的影响 接触酒精对学业发展和进步的影响 问题、犯罪以及药物使用和滥用。 我们将评估 先前心理和心理差异的纵向影响 身体发育、气质、心理状态、活动 水平、学习成绩、行为问题、环境以及 产前酒精暴露对青少年酒精和其他药物的影响 使用。