PEDIATRIC STUDY CENTERS (PSCS) FOR A MRI STUDY OF NORMAL

儿科研究中心 (PSCS) 对正常儿童进行 MRI 研究

• 批准号: 6358420
• 负责人: ROBERT C MCKINSTRY
• 金额: $ 10.62万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-09-30 至 2005-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6358420
• 关键词: adolescence (12-20); behavior test; behavioral /social science research tag; bioimaging /biomedical imaging; biomedical resource; child (0-11); child behavior; clinical research; cognition; cooperative study; developmental neurobiology; diffusion; human subject; information systems; longitudinal human study; magnetic resonance imaging; nuclear magnetic resonance spectroscopy; pediatrics; water

This is a multi-center study of normal structural and metabolic brain development in infants and children, being sponsored by NINDS, NIMH and NICHD. Magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS) will be used to characterize brain development in relationship to behavior and cognition from ages 0 through 18 years, supplemented by diffusion tensor imaging (DTI) for ages 0 through 4 years. The project is planned for six years and involves a longitudinal design, repeated behavioral testing, and rescanning of subjects. This project will result in a representative, reliable and adequate database with which to characterize normal brain development, construct growth curves with which to evaluate individual brains, provide potential control data for studies of patients, and create developmentally-sensitive image analysis tools. A data sharing plan will be implemented to make this resource available to the medical and research community.

这是一项由Ninds，Nimh和Nichd赞助的婴儿和儿童正常结构和代谢脑发育的多中心研究。 磁共振成像（MRI）和磁共振光谱（MRS）将用于表征与0至18岁年龄段的行为和认知关系的脑发育，并补充了0至4岁的扩散张量张量成像（DTI）。 该项目计划了六年，涉及纵向设计，重复的行为测试和对受试者的撤销。该项目将导致一个代表性，可靠和适当的数据库来表征正常的大脑发育，构建生长曲线，以评估单个大脑，为患者的研究提供潜在的控制数据，并创建对发育敏感的图像分析工具。 将实施一个数据共享计划，以使医学和研究社区可用此资源。