DEVELOPMENT OF SECOND GENERATION FLUORESCENCE EEM SYSTEM

第二代荧光EEM系统的研制

• 批准号: 6281760
• 负责人: RAMASAMY MANOHARAN
• 金额: $ 2.27万
• 依托单位: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-06-01 至 1999-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6281760
• 关键词: bioengineering /biomedical engineering; biomedical equipment development; biomedical resource; building /facility design /renovation; clinical research; human tissue; spectrometry; technology /technique; women's health

We are continuously improving our current in vivo EEM system which can collect 10 fluorescence spectra excited with 10 different light sources and diffuse reflectance spectra from the same tissue in less than a second. The improvements are being carried out in three areas: (a) use of stepper motor to access invidual excitation wavelengths when needed and also accumulate multi-pulse fluorescence data, (b) use of compact high sensitive CCD detector especially important in collecting data from cancerous tissue sites which are inherently weaker emitters, (c) simply the electronics, make it portable and easy to use.

我们一直在不断改善当前的体内EEM系统 可以收集10种不同光激发的10个荧光光谱 来自同一组织的来源和弥漫性反射光谱较少 比一秒钟。 改进正在三个领域进行： （a）使用步进电机来访问不景气的激发波长 在需要时并累积多脉冲荧光数据，（b）使用 紧凑的高灵敏的CCD检测器尤其重要 从固有的癌组织部位收集数据 发射器较弱，（C）简单 使用。