Towards licensing of lab on chip technologies for water quality and environmental metrology markets

争取水质和环境计量市场的芯片实验室技术许可

基本信息

批准号：
NE/M021858/1
负责人：
Matt Mowlem
金额：
$ 25.42万
依托单位：
NATIONAL OCEANOGRAPHY CENTRE
依托单位国家：
英国
项目类别：
Research Grant
财政年份：
2015
资助国家：
英国
起止时间：
2015 至无数据
项目状态：
已结题

来源：
https://gtr.ukri.org/projects?ref=NE%2FM021858%2F1
关键词：
Towards licensing lab chip technologies

项目摘要

This project will develop the commercial potential of lab on chip chemical sensor technologies developed by the National Oceanography Centre Southampton, and the University of Southampton. The lab on a chip sensors work by mixing sample water with a reagent that reacts to form a coloured product with intensity of colour proportional to the target chemical. For example Nitrite mixed with the Griess reagent forms a distinctive pink colour. This mixing is performed in a polymer "chip" in which channels approximately 0.15 mm in diameter are formed. Sample and reagent are moved through these channels with syringe pumps and controlled by miniature valves operated by electromagnetic solenoids, all under software control from bespoke electronics. The intensity of colour and hence the concentration of the chemical is also measured on the "chip" using LEDs and detectors glued into it. The whole system is extremely robust as it has been designed for operation in the deep sea. The systems are now routinely deployed to support NERC science (e.g. in the Macronutrient Cycles Programme). The robustness and excellent performance achieved mean there has been considerable commercial interest from companies looking to manufacture and sell the sensors. We and our commercial contacts estimate that the addressable market, which includes applications outside the marine sector, is approximately £64M/yr. To maximise the commercial potential, and to realise this potential we are seeking to partner with a company via a license agreement. For this to be signed, we need to prove the technology in field trials and demonstrations with the potential licensee(s), improve our documentation, and make some adaptations to the marine sensors so they are more suitable for all the target market applications. These adaptations include allowing function in a wider range of temperatures, where waters are fresh but more turbid (muddy) or where biological fouling is more significant. To recruit potential licensees we will initially work with companies with which we are already in contact but will also publicise the product through workshops at existing industry meetings or exhibitions, at conferences and through publishing in journals read by industry and key user groups.

该项目将开发由国家海洋学中心南安普敦和南安普敦大学开发的芯片化学传感器技术实验室的商业潜力。芯片传感器上的实验室通过将样品水与试剂混合起来，该试剂反应形成与目标化学物质成正比的有色产物。例如，亚硝酸盐与Griess试剂混合形成独特的粉红色。这种混合在聚合物“芯片”中进行，其中形成直径约0.15 mm的通道。样品和试剂用注射泵通过这些通道移动，并由电子电磁阀操作的微型阀控制，所有这些阀都受到定制电子产品的软件控制。颜色的强度以及化学物质的浓度也可以在“芯片”上使用LED和粘在其中的检测器进行测量。整个系统非常强大，因为它是为在深海运行而设计的。现在，该系统通常部署以支持NERC科学（例如在大量营养素周期计划中）。实现的稳健性和出色的表现意味着希望制造和出售传感器的公司具有很大的商业兴趣。我们和我们的商业联系人估计，可寻址市场包括海洋领域以外的申请，约为6400万英镑/年。为了最大程度地发挥商业潜力，并实现这一潜力，我们正在寻求通过许可协议与公司合作。为此，我们需要在现场试验和示范中证明与潜在被许可人的示范，改进我们的文档，并对海洋传感器进行一些改编，以便它们更适合所有目标市场应用。这些适应包括允许在广泛的温度下进行功能，其中水是新鲜的，但更浑浊（泥泞）或生物结垢更为重要。为了招募潜在的许可，我们最初将与已经联系的公司合作，还将通过现有行业会议或展览，会议和通过行业和主要用户群体阅读的期刊上发布的讲习班来发布产品。

项目成果

期刊论文数量（6）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Handbook of Optoelectronics: Applied Optical Electronics (Volume Three)

光电子学手册：应用光电子学（第三卷）

DOI：
发表时间：
2017
期刊：
影响因子：
0
作者：
Mowlem, M
通讯作者：
Mowlem, M

Evaluation of a Ferrozine Based Autonomous in Situ Lab-on-Chip Analyzer for Dissolved Iron Species in Coastal Waters

DOI：
10.3389/fmars.2017.00322
发表时间：
2017-01-01
期刊：
FRONTIERS IN MARINE SCIENCE
影响因子：
3.7
作者：
Geissler, Felix;Achterberg, Eric P.;Connelly, Douglas P.
通讯作者：
Connelly, Douglas P.

Advancing Observation of Ocean Biogeochemistry, Biology, and Ecosystems With Cost-Effective in situ Sensing Technologies

利用具有成本效益的原位传感技术推进海洋生物地球化学、生物学和生态系统的观测

DOI：
10.3389/fmars.2019.00519
发表时间：
2019
期刊：
Frontiers in Marine Science
影响因子：
3.7
作者：
Wang, Zhaohui Aleck;Moustahfid, Hassan;Mueller, Amy V.;Michel, Anna P.;Mowlem, Matthew;Glazer, Brian T.;Mooney, T. Aran;Michaels, William;McQuillan, Jonathan S.;Robidart, Julie C.
通讯作者：
Robidart, Julie C.

Industry Partnership: Lab on Chip Chemical Sensor Technology for Ocean Observing