Lab. Animal

实验室。

基本信息

批准号：
7714423
负责人：
Sandra Sexton
金额：
$ 14.16万
依托单位：
ROSWELL PARK CANCER INSTITUTE CORP
依托单位国家：
美国
项目类别：
财政年份：
2008
资助国家：
美国
起止时间：
2008-07-28 至 2013-04-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7714423
关键词：
Accreditation Adopted Air American Animal Care and Use Committees Animal Experimentation Animal Husbandry Animal Technicians Animals Antineoplastic Agents Ascites Backcrossings Beds Budgets Cancer Center Support Grant Canis familiaris Carcinogens Caring Certification Collection Complex Cost Control Crossbreeding Daily Decontamination Development Diagnostic Ensure Environment Equipment and supply inventories Faculty Food Funding Grant Health Health Services Research Horizontal Disease Transmission Human Resources Hybridomas Image Immune Incineration Institutes International Knockout Mice Laboratories Laboratory Animal Medicine Laboratory Animal Science Laboratory Animals Licensing Livestock Maintenance Medical Medical Research Medical Surveillance Modeling Mus New York Peer Review Procedures Process Production Protocols documentation Rattus Registries Research Personnel Residencies Resources Rodent Safety Services Standards of Weights and Measures Sterility Stream Techniques Technology Training Training Programs Transgenic Organisms Veterinarians Water Woodchuck Work animal care animal resource cancer cell cost effective foot human disease irradiation knockout gene laboratory facility member monoclonal antibody production mouse model mutant pathogen prevent programs tool tumor wasting

Accreditation Adopted Air American Animal Care and Use Committees Animal Experimentation Animal Husbandry Animal Technicians Animals Antineoplastic Agents Ascites Backcrossings Beds Budgets Cancer Center Support Grant Canis familiaris Carcinogens Caring Certification Collection Complex Cost Control Crossbreeding Daily Decontamination Development Diagnostic Ensure Environment Equipment and supply inventories Faculty Food Funding Grant Health Health Services Research Horizontal Disease Transmission Human Resources Hybridomas Image Immune Incineration Institutes International Knockout Mice Laboratories Laboratory Animal Medicine Laboratory Animal Science Laboratory Animals Licensing Livestock Maintenance Medical Medical Research Medical Surveillance Modeling Mus New York Peer Review Procedures Process Production Protocols documentation Rattus Registries Research Personnel Residencies Resources Rodent Safety Services Standards of Weights and Measures Sterility Stream Techniques Technology Training Training Programs Transgenic Organisms Veterinarians Water Woodchuck Work animal care animal resource cancer cell cost effective foot human disease irradiation knockout gene laboratory facility member monoclonal antibody production mouse model mutant pathogen prevent programs tool tumor wasting

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项目摘要

The Laboratory Animal Resource is responsible for promoting the humane care of laboratory animals used by CCSG investigators. In June 2005, the Association for the Assessment and Accreditation of Laboratory Animal Care International (AAALAC International) reviewed and re-accredited the Resource for a full three years. The Resource provides specialized animal husbandry; veterinary medical care; animal health surveillance; diagnostic laboratory facilities; irradiation services, research technical services, and faculty training to support more than 150 Institute Animal Care and Use Committee (IACUC) -approved animal use protocols. Additional services include immune-deficient rodent production, imaging facilities, import and export of animals, and hybridoma ascites production and collection in mice. Daily animal inventories of 24,000 to 28,000 include primarily rodents, but also include woodchucks, dogs and occasionally farm animals. The Resource Director is a New York State licensed veterinarian who completed a residency-training program in Laboratory Animal Medicine. Eighteen members of the technical staff are certified through the Certification and Registry Board of the American Association for Laboratory Animal Science (AALAS). The Laboratory Animal Resource is located in the four-story 39,000 net square feet (nsf) Vivarium, which opened in 1998, is adjacent to the Medical Research Complex (MRC). An additional 8,000 nsf of newly renovated space is available in the Cancer Cell Center. Laboratories for work with gene knockout and transgenic technologies in mice are immediately adjacent to animal holding rooms. Continued support through the CCSG will permit the Resource to provide a standard of care and use that meets or exceeds applicable state and federal standards, maintain full AAALAC International accreditation, and furnish investigators with a comprehensive program for safe, appropriate and cost effective research animal use. The Laboratory Animal Resource serves investigators from all six CCSG programs and offers continuing training opportunities to enhance animal safety and resource usage. The Resource remains an important tool for recruitment and retention of peer-reviewed investigators due to high efficiency, dedicated well-trained staff and low chargebacks to investigators made possibly by RPCI subsidy. Over the last grant period, CCSG Developmental funds were allocated to expand a new and unique service titled, Mouse Tumor Model Resource (MTMR). The MTMR provides services for specialized techniques, as well as mouse models of human disease. The Resource is used by all six CCSG Programs and 93% of users are CCSG members. $168,487 in CSCG support is requested, representing 6% of the total operating budget.

实验室动物资源负责促进实验动物的人道护理 CCSG调查人员使用。 2005年6月，评估和认证协会实验室动物护理国际（AAAALAC国际）审查并重新获得了A的资源整整三年。该资源提供了专业的畜牧业；兽医医疗；动物健康监测；诊断实验室设施；辐照服务，研究技术服务以及教师培训以支持150多个研究所动物护理委员会（IACUC）批准动物使用方案。其他服务包括免疫缺陷的啮齿动物生产，成像设施，动物的进口和出口，以及小鼠杂交瘤的产生和收集。每日动物 24,000至28,000的库存主要包括啮齿动物，但还包括木屋，狗和偶尔养殖动物。资源总监是纽约州许可的兽医，他完成了居住培训实验室动物医学计划。十八位技术人员通过美国实验室动物科学协会（AALAS）认证和注册委员会。这实验室动物资源位于开放的四层楼39,000净平方英尺（NSF）的Vivarium 1998年，医学研究综合体（MRC）毗邻。另外8,000 nsf的新装修癌细胞中心可用空间。与基因淘汰和转基因一起工作的实验室小鼠的技术紧邻动物饲养室。继续通过 CCSG将允许资源提供符合或超过适用状态的护理和使用标准以及联邦标准，维持全面的AAAALAC国际认证，并为调查人员提供综合计划，以实现安全，适当和具有成本效益的研究动物使用。实验室动物资源为所有六个CCSG计划的调查人员提供服务，并提供继续培训机会，以增强动物的安全和资源使用。资源仍然是由于高效率，专用于同行评审研究人员的重要工具训练有素的员工和RPCI补贴可能对调查人员的低退款。在上一个赠款期间，CCSG的发展基金被分配以扩展新的独特服务标题为“小鼠肿瘤模型资源（MTMR）”。 MTMR为专业提供服务技术以及人类疾病的小鼠模型。所有六个CCSG程序都使用该资源，而93％的用户是CCSG成员。 $ 168,487 在CSCG支持中，请求，占总运营预算的6％。