GORDON RESEARCH CONFERENCE ON LYSOSOMES

戈登溶酶体研究会议

• 批准号: 6158878
• 负责人: SCOTT D EMR
• 金额: $ 0.7万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-06-15 至 2001-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6158878
• 关键词: intracellular transport; lysosomes; meeting /conference /symposium; travel

DESCRIPTION (taken from the application) Funds are requested to support domestic travel and conference fees for U.S.-based speakers at the 19th Lysosome Gordon Conference to be held June 25 to June 30, 2000 at the Proctor Academy, Andover, NH. The conference provides a unique opportunity for formal oral and poster presentations, as well as informal discussions aimed at stimulating research on topics related to membrane trafficking in the endosomal-lysosomal system in normal and pathological conditions. Rapid progress in this field will enable discussions on the molecular mechanisms of endocytosis and lysosomal targeting, as well as the role of endosomes and lysosomes in processes such as synaptic transmission, bacterial pathogenesis, parasite-host interactions, antigen presentation, regulation of insulin-responsiveness, control of cellular proliferation. Sessions will include: 1. The structure of the endocytic machinery. 2. Mechanisms of endocytosis. 3. Transport and sorting in the endocytic pathway. 4 Vesicle budding and fusion in the endosomal-lysosomal system. 5. Protein sorting at the TGN. 6. Lysosome function and dynamics. 7. The yeast vacuole. 8. Disorders of lysosome biogenesis and function. These sessions will provide up-to-date information of direct relevance to a variety of disease-related topics, including neurological disorders, bacterial and parasitic diseases, diabetes, immunological diseases, vaccine development, lysosomal storage disorders, pigmentation and blood clotting disorders. Because of this relevance to translational clinical research, this meeting is regularly attended by medical researchers interested in the development of new therapeutic avenues. Speakers will include many recognized world leaders in this field, as well as younger investigators. One third of the speakers and session chairs are female, reflecting closely the demography of this area of research. The goal of the Conference is to provide a forum for the free exchange of new findings so as to generate new ideas and collaborations among scientists from a variety of backgrounds.

描述（摘自申请表） 需要资金支持国内旅行和会议费用 将于 6 月 25 日至 30 日举行的第 19 届溶酶体戈登会议上的美国发言人， 2000 年在新罕布什尔州安多弗普罗克特学院。此次会议提供了独特的 正式口头和海报展示以及非正式的机会 旨在促进膜相关主题研究的讨论 正常和病理状态下内体-溶酶体系统的运输 状况。该领域的快速进展将使有关以下问题的讨论成为可能： 内吞作用和溶酶体靶向的分子机制，以及 内体和溶酶体在突触传递等过程中的作用， 细菌发病机制、寄生虫-宿主相互作用、抗原呈递、 调节胰岛素反应性，控制细胞增殖。 会议内容包括： 1. 内吞机制的结构。 2. 内吞作用的机制。 3.内吞途径中的运输和分选。 4 内体-溶酶体系统中的囊泡出芽和融合。 5. 蛋白质 在 TGN 进行排序。 6. 溶酶体功能和动力学。 7.酵母液泡。 8. 溶酶体生物发生和功能障碍。这些会议将提供 与各种疾病相关的直接相关的最新信息 主题，包括神经系统疾病、细菌和寄生虫病， 糖尿病、免疫疾病、疫苗开发、溶酶体储存 疾病、色素沉着和凝血障碍。由于这种相关性 对于转化临床研究，该会议定期参加 对开发新治疗途径感兴趣的医学研究人员。 演讲者将包括该领域许多公认的世界领导人，以及 年轻的调查员。三分之一的演讲者和会议主席是女性， 密切反映了该研究领域的人口统计学。的目标 会议旨在提供一个自由交流新发现的论坛，以便 来自不同领域的科学家之间产生新的想法和合作 背景。