NIDA STRENGTHENING WASHINGTON, DC FAMILIES GRANT

NIDA 加强华盛顿特区家庭补助金

• 批准号: 6164457
• 负责人: KAROL L. KUMPFER
• 金额: $ 77.36万
• 依托单位: UNIVERSITY OF UTAH
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-03-01 至 2003-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6164457
• 关键词: clinical research; clinical trials; computational neuroscience; drug abuse education; drug abuse information system; drug abuse prevention; education evaluation /planning; family structure /dynamics; health care cost /financing; human subject; longitudinal human study; mathematical model; middle childhood (6-11); parent offspring interaction; racial /ethnic difference; social model; statistics /biometry; training

DESCRIPTION: (Applicant's Abstract) The goal of this five year research is to provide new knowledge on: 1) the causes of drug use and abuse in inner city African-American and White adolescents, and 2) the most cost-effective and cost-beneficial family-focused prevention interventions. The research aims of this randomized clinical trial involving over 800 at-risk Washington, D.C.-area families of 7 to 11 year olds in components of the 16 week Strengthening Families Program (SFP) are: 1) to test the differential efficacy of the three major components of SFP-parent training (PT), children's skills training (CT), and family skills training (FT) compared to a minimal contact control (MT) on precursors and substance use/abuse employing a 2 x 4 experimental design; 2) to estimate the cost-benefit and cost-effectiveness of the SFP components with 400 African American families and 400 White families; and 3) to empirically test several competing etiological and intervention theories of drug use/abuse underlying the intervention design by analyzing the survey research data from 1,600 12 to 19 year olds and the 800 intervention families using structural equation modeling, mediational analysis, hierarchical linear modeling, latent growth modeling, and transactional modeling (cross-lagged SEM, artificial intelligence, and neural network simulations) for gender, race, and other sub-groups. The rationale for the component design is that a major question exists concerning the efficacy of child-only interventions that group high-risk children together as well as the added benefit of working with the family together compared to parent-training only. Demonstrating the importance of involving parents and working with families would be very valuable information for prevention providers. Additional co-variate outcome analyses will be conducted to answer practical questions conceming the efficacy of the four interventions for different subgroups of clients. A strong process evaluation including a management information system (MIS) conducted by University of Maryland researchers wili document implementation process and provide feedback to improve implementation fidelity. Additional health services sub-aim questions will be addressed through analyses of recruitment, attrition, consumer satisfaction, participation variables, and client and trainer characteristics linked to outcomes. Seven nationally recognized consultants have agreed to support the culturally-specific program development, implementation, and data analyses.

描述：（申请人的摘要） 这项五年研究的目的是提供有关：1） 非裔美国人和白人毒品使用和滥用毒品的原因 青少年和2）最具成本效益和成本效益 以家庭为中心的预防干预措施。 研究目的 随机临床试验，涉及800多个处于危险的华盛顿特区 - 地区 在16周加强的组成部分中，有7至11岁的家庭 家庭计划（SFP）是：1）测试 SFP父母培训（PT）的三个主要组成部分，儿童的技能 与最小的接触相比，培训（CT）和家庭技能培训（FT） 使用2 x 4的前体和药物使用/滥用的控制（MT） 实验设计； 2）估计成本效益和成本效益 SFP组件有400个非洲裔美国家庭和400个白色 家庭； 3）经验测试几种竞争性的病因和 干预设计的毒品使用/滥用的干预理论 通过分析1,600 12至19岁的调查研究数据和 800干预家庭使用结构方程建模，中介 分析，分层线性建模，潜在增长建模和 交易建模（交叉隔离SEM，人工智能和 神经网络模拟）性别，种族和其他子群体。 这 组件设计的理由是存在一个主要问题 关于将高风险分组的仅儿童干预措施的功效 儿童在一起以及与家人合作的额外好处 与父母培训相比，共同在一起。 证明了重要性 参与父母并与家人合作将非常有价值 预防提供者的信息。 附加的共同结果 分析将进行回答，以回答实用问题 这四个干预措施对客户的不同亚组的功效。 一个 强大的流程评估，包括管理信息系统（MIS） 马里兰大学研究人员Wili文件实施 处理并提供反馈以提高实施保真度。 额外的 卫生服务子AIM问题将通过分析来解决 招聘，流失，消费者满意度，参与变量以及 客户和培训师特征与结果相关。 全国七个 公认的顾问已同意支持特定于文化的顾问 计划开发，实施和数据分析。