DEVELOPMENT OF MICROCALORIMETERS FOR THE STUDY OF BIOLOGICAL REACTIONS

用于生物反应研究的微热量计的开发

• 批准号: 3858013
• 负责人: R L BERGER
• 金额: --
• 依托单位: NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3858013
• 关键词: bioengineering /biomedical engineering; biomedical equipment development; chemical binding; chemical reaction; endotoxins; heat; hemoglobin; ionic bond; ligands; lipopolysaccharides; mathematics; microcalorimetry; reagent /indicator; thermodynamics

The tantalum stopped-flow microcalorimeter has been utilized this year in the initiating of studies of isoionic binding studies, both of ligand and effector molecules, and for the study of the study of the binding of endotoxin (lipid polysaccharide to hemoglobin. Various improvements in the ease of operation of the calorimeter and to its versatility have been initiated as a result of suggestions from several researchers using the instrument. The new pulsed heat capacity calorimeter has been improved considerably and the mathematics worked out for the simultaneous measurement of both the heat capacity and thermal conduction of a liquid sample.

钽停流微量热计今年已在 启动配体和等离子结合研究 效应分子，以及用于结合的研究 内毒素（脂质多糖到血红蛋白。各种改进 热量计的操作简便性及其多功能性 根据几位研究人员的建议而发起，使用 乐器。 改进了新型脉冲热容热量计 相当大，数学计算出同时 液体热容和热导率的测量 样本。