PURCHASE OF A HIGH SENSITIVITY PROTEIN SEQUENCER

购买高灵敏度蛋白质测序仪

• 批准号: 2487488
• 负责人: W Todd MILLER
• 金额: $ 13.28万
• 依托单位: STATE UNIVERSITY NEW YORK STONY BROOK
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-03-18 至 1999-03-17
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2487488
• 关键词: biomedical equipment purchase; protein sequence

Funds are requested for the acquisition of a high sensitivity, rapid throughput protein sequencer for the sequence analysis of proteins and peptides. The instrument will be housed in the Center for the Analysis and Synthesis of Macromolecules (CASM) in the Department of Physiology & Biophysics at Stony Brook, and operated as a shared facility overseen by the School of Medicine and the Center for Biotechnology. Projects will be conducted by eight major faculty, and as many as twenty other faculty users from the departments of Physiology & Biophysics, Medicine, Biochemistry, Chemistry, Oral Biology & Pathology, and other departments whose research requires the sequence analysis of proteins and peptides. Samples to be analyzed include covalent protein-ligand complexes, glycopeptides, phosphopeptides, photoaffinity modified peptides, and peptides from enzymatic digests of posttranslationally-modified proteins.

需要资金来购买高灵敏度、快速的 用于蛋白质序列分析的通量蛋白质测序仪 肽。 该仪器将安置在分析中心 生理学系高分子与合成（CASM） 石溪生物物理学中心，作为共享设施运营，由 医学院和生物技术中心。 项目将 由八个主要教师和多达二十个其他教师进行 来自生理学和生物物理学、医学等部门的用户， 生物化学、化学、口腔生物学与病理学等科室 其研究需要蛋白质和肽的序列分析。 待分析的样品包括共价蛋白质-配体复合物， 糖肽、磷酸肽、光亲和修饰肽和 来自翻译后修饰蛋白质的酶消化的肽。