CORE--IMMUNOLOGY

核心--免疫学

• 批准号: 6100222
• 负责人: DAVID D HO
• 金额: --
• 依托单位: AARON DIAMOND AIDS RESEARCH CENTER
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-05-15 至 1999-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6100222
• 关键词: AIDS vaccines; antibody neutralization test; antibody titering; biomedical facility; cell line; cellular immunity; cytokine; cytotoxic T lymphocyte; human immunodeficiency virus; immunocytochemistry; immunologic assay /test; microorganism immunology; mucosal immunity; simian immunodeficiency virus

Infection with HIV, SIV, and administration of vaccines based upon their components, elicit specific humoral and cellular immune responses. The quantitation of these responses, and the identification of antigenic epitopes recognized by specific effector mechanisms, are crucial to the success of the projects described in this PO1. The overall objective of the Immunology Core is to provide comprehensive immunologic services, reagents, and facilities to members of ADARC, thereby facilitating evaluation of the immunological properties of candidate vaccines.

艾滋病毒，SIV感染和疫苗给药 成分，引起特定的体液和细胞免疫反应。这 这些反应的定量以及抗原的鉴定 特定效应器机制认可的表位对 该PO1中描述的项目的成功。总体目标 免疫学核心是提供全面的免疫服务， 试剂和ADARC成员的设施，从而促进 评估候选疫苗的免疫学特性。