Ultrahigh throughput total transcriptomics
超高通量全转录组学
基本信息
- 批准号:EP/Y032756/1
- 负责人:
- 金额:$ 16.19万
- 依托单位:
- 依托单位国家:英国
- 项目类别:Research Grant
- 财政年份:2023
- 资助国家:英国
- 起止时间:2023 至 无数据
- 项目状态:未结题
- 来源:
- 关键词:
项目摘要
Having submitted a patent (supported by CambridgeEnterprise, UCAM's technology transfer office) we now want to explore a detailed commercialization pathway, including a strategy totarget markets and customers, further exploration of the IP landscape and draft business plans for various scenarios to quantify theirviability as revenue streams. In proof-of concept experiments we will increase throughput and data quality to assess and showcasethe future potential of VASA-drop in an extended microfluidic workflow. Finally we will define a new area of application by exploringhow VASA-drop can be used as a quality control readout for cell culture experiments.
提交专利(由 UCAM 技术转让办公室 CambridgeEnterprise 支持)后,我们现在希望探索详细的商业化途径,包括针对市场和客户的战略、进一步探索知识产权格局以及起草各种场景的商业计划,以将其可行性量化为收入溪流。在概念验证实验中,我们将提高吞吐量和数据质量,以评估和展示 VASA-drop 在扩展微流体工作流程中的未来潜力。最后,我们将通过探索如何将 VASA-drop 用作细胞培养实验的质量控制读数来定义一个新的应用领域。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Florian Hollfelder其他文献
Growth amplification in ultrahigh-throughput microdroplet screening increases sensitivity of clonal enzyme assays and minimizes phenotypic variation
- DOI:
10.1039/d0lc00830c - 发表时间:
2020-11 - 期刊:
- 影响因子:6.1
- 作者:
Paul Jannis Zurek;Raphaëlle Hours;Ursula Schell;Ahir Pushpanath;Florian Hollfelder - 通讯作者:
Florian Hollfelder
Divergent synthesis of biflavonoids yields novel inhibitors of the aggregation of amyloid β (1–42)
- DOI:
10.1039/c7ob00804j - 发表时间:
2017-05 - 期刊:
- 影响因子:3.2
- 作者:
Tze Han Sum;Tze Jing Sum;Súil Collins;Warren R. J. D. Galloway;David G. Twigg;Florian Hollfelder;David R. Spring - 通讯作者:
David R. Spring
Microfluidic platform for 3D cell culture with live imaging and clone retrieval
- DOI:
10.1039/d0lc00165a - 发表时间:
2020-06 - 期刊:
- 影响因子:6.1
- 作者:
Carla Mulas;Andrew C. Hodgson;Timo N. Kohler;Chibeza C. Agley;Peter Humphreys;Hans Kleine-Brüggeney;Florian Hollfelder;Austin Smith;Kevin J. Chalut - 通讯作者:
Kevin J. Chalut
Thermostable in vitro transcription-translation compatible with microfluidic droplets
与微流体液滴兼容的热稳定性体外转录翻译
- DOI:
10.1186/s12934-024-02440-y - 发表时间:
2024-06-10 - 期刊:
- 影响因子:6.4
- 作者:
Ana L. J. L. Ribeiro;Patricia Pérez;Mercedes Sánchez;Lara Pérez;Marcos Almendros;Liisa D. van Vliet;Fabrice Gielen;Jesmine Lim;Simon Charnock;Florian Hollfelder;J. González;José Berenguer;Aurelio Hidalgo - 通讯作者:
Aurelio Hidalgo
Acoustic sorting of microfluidic droplets at kHz rates using optical absorbance
- DOI:
10.1039/d2lc00871h - 发表时间:
2022-12 - 期刊:
- 影响因子:6.1
- 作者:
Esther S. Richter;Andreas Link;John S. McGrath;Raymond W. Sparrow;Maximilian Gantz;Elliot J. Medcalf;Florian Hollfelder;Thomas Franke - 通讯作者:
Thomas Franke
Florian Hollfelder的其他文献
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{{ truncateString('Florian Hollfelder', 18)}}的其他基金
Novel Plastizymes: discovery and improvement of plastic-degrading enzymes by integrated cycles of computational and experimental approaches
新型塑料酶:通过计算和实验方法的综合循环发现和改进塑料降解酶
- 批准号:
BB/X00306X/1 - 财政年份:2023
- 资助金额:
$ 16.19万 - 项目类别:
Research Grant
Mapping the overlapping fitness landscapes of a superfamily of promiscuous enzymes: strategies for directed evolution?
绘制混杂酶超家族的重叠适应度景观:定向进化策略?
- 批准号:
BB/W000504/1 - 财政年份:2022
- 资助金额:
$ 16.19万 - 项目类别:
Research Grant
CAZyme evolution and discovery: Ultrahigh throughput screening of carbohydrate-active enzymes in modular assays modular based on coupled reactions
CAZyme 的演变和发现:基于耦合反应的模块化测定中碳水化合物活性酶的超高通量筛选
- 批准号:
BB/W006391/1 - 财政年份:2022
- 资助金额:
$ 16.19万 - 项目类别:
Research Grant
Biocatalysis by plastic-degrading enzymes for bioremediation and recycling
塑料降解酶的生物催化用于生物修复和回收
- 批准号:
EP/X03464X/1 - 财政年份:2022
- 资助金额:
$ 16.19万 - 项目类别:
Research Grant
SENSE - Screening of ENvironmental SEquences to discover novel protein functions using informatics target selection and high-throughput validation
SENSE - 使用信息学目标选择和高通量验证筛选环境序列以发现新的蛋白质功能
- 批准号:
BB/T003545/1 - 财政年份:2020
- 资助金额:
$ 16.19万 - 项目类别:
Research Grant
Towards Novel Glycoside Hydrolases
迈向新型糖苷水解酶
- 批准号:
BB/L002469/1 - 财政年份:2014
- 资助金额:
$ 16.19万 - 项目类别:
Research Grant
New detection modes for droplet microfluidics
液滴微流控的新检测模式
- 批准号:
BB/K013629/1 - 财政年份:2013
- 资助金额:
$ 16.19万 - 项目类别:
Research Grant
Exploring the Potential of Networked Directed Evolution Based on Novel LacI/effector Pairs
探索基于新型 LacI/效应器对的网络化定向进化的潜力
- 批准号:
BB/J008214/1 - 财政年份:2012
- 资助金额:
$ 16.19万 - 项目类别:
Research Grant
Catalytic promiscuity in a protein superfamily
蛋白质超家族中的催化混杂
- 批准号:
BB/I004327/1 - 财政年份:2011
- 资助金额:
$ 16.19万 - 项目类别:
Research Grant
Bronsted Analysis of Catalytic Promicuity in Enzyme Models and Model Enzymes
酶模型和模型酶中催化相似性的布朗斯台德分析
- 批准号:
EP/E019390/1 - 财政年份:2007
- 资助金额:
$ 16.19万 - 项目类别:
Research Grant
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