CANCER CONTROL RESEARCH UNIT FOR CT AT YALE

耶鲁大学 CT 癌症控制研究中心

• 批准号: 2090594
• 负责人: JAN A STOLWIJK
• 金额: $ 46.03万
• 依托单位: YALE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-04-01 至 1995-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2090594
• 关键词: behavioral medicine; cancer prevention; neoplasm /cancer diagnosis; neoplasm /cancer epidemiology

This CCRU is a collaborative arrangement between Yale University, the University of Connecticut, and the Connecticut Department of Health Services. The State of Connecticut, under active cancer surveillance by the Connecticut Tumor Registry and the SEER program, is the population resource for our program. Our major theme is the improvement of screening methods for early detection of cancer through the use of epidemiological, clinical, laboratory, and behavioral sciences. This program takes advantage of the scientific strengths that already exist within the medical institutions of our State. We have also sought to involve investigators who have made major scientific contributions in related fields, but who are new to the field of cancer control research. While our principle projects focus on critical aspects of early detection, we also include studies that are designed to provide the basis for future research on techniques for control of colon cancer and a Beta-Carotene study aimed at improved management for early stage head and neck cancer patients. We continue to develop our paired community research potential with studies in Connecticut and Long Island, N.Y. Our research program has two special qualities. 1) The majority of our intervention studies are population based, facilitating generalization to other areas of the country. 2) The initial impact of improvements in early detection rates that are monitored through the cancer registries. The long-term nature of the data of the Connecticut Tumor Registry enhances the ability to detect departures from existing trend in cancer incidence and mortality. The combinations of disciplines represented in this proposal plus the unique resources available in this region provides a foundation for a exemplary cancer control research unit.

该 CCRU 是耶鲁大学、 康涅狄格大学和康涅狄格卫生部 服务。 康涅狄格州正在积极进行癌症监测 康涅狄格州肿瘤登记处和 SEER 计划，是人口 我们的计划的资源。 我们的主题是改进 通过使用以下方法早期发现癌症的筛查方法 流行病学、临床、实验室和行为科学。 该计划利用了已经存在的科学优势 存在于我国医疗机构内。 我们也曾寻求过 让做出重大科学贡献的研究人员参与进来 相关领域，但对癌症控制研究领域不熟悉。 虽然我们的主要项目侧重于早期的关键方面 检测，我们还包括旨在提供 为未来结肠癌控制技术研究奠定基础 一项旨在改善早期头部管理的β-胡萝卜素研究 以及颈部癌症患者。 我们继续发展我们的配对社区 康涅狄格州和纽约长岛的研究潜力 我们的研究计划有两个特点。 1）我们的大多数 干预研究以人群为基础，有利于推广 到该国其他地区。 2) 改进的初步影响 通过癌症监测的早期检测率 注册表。 康涅狄格州肿瘤数据的长期性质 注册中心增强了检测现有趋势背离的能力 癌症发病率和死亡率。 该提案中所代表的学科组合加上 该地区独特的资源为我们的发展奠定了基础 模范癌症控制研究单位。

项目成果

Alcohol and tobacco use prediagnosis and postdiagnosis, and survival in a cohort of patients with early stage cancers of the oral cavity, pharynx, and larynx.

• DOI: 10.1158/1055-9965.epi-09-0944
• 发表时间: 2009-12
• 期刊: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
• 作者: Mayne ST;Cartmel B;Kirsh V;Goodwin WJ Jr
• 通讯作者: Goodwin WJ Jr

Cancer-specific beliefs and survival: a population-based study of African-American and White breast cancer patients.

癌症特异性信念和生存：针对非裔美国人和白人乳腺癌患者的一项基于人群的研究。

• DOI: 10.1007/s10552-004-2232-4
• 发表时间: 2005
• 期刊: Cancer causes & control : CCC.
• 作者: Soler-Vila,Hosanna;Kasl,StanislavV;Jones,BethA
• 通讯作者: Jones,BethA

Antioxidant nutrients and cancer incidence and mortality: an epidemiologic perspective.

抗氧化营养素与癌症发病率和死亡率：流行病学视角。

• DOI: 10.1016/s1054-3589(08)61004-2
• 发表时间: 1997
• 期刊: Advances in pharmacology (San Diego, Calif.)
• 作者: Mayne,ST

Tumor vascularity is not a prognostic factor for malignant melanoma of the skin.

肿瘤血管分布不是皮肤恶性黑色素瘤的预后因素。

• 发表时间: 1995
• 期刊: The American journal of pathology.
• 作者: Busam,KJ;Berwick,M;Blessing,K;Fandrey,K;Kang,S;Karaoli,T;Fine,J;Cochran,AJ;White,WL;Rivers,J
• 通讯作者: Rivers,J

Time trend and age-period-cohort effects on incidence of esophageal cancer in Connecticut, 1935-89.

康涅狄格州食管癌发病率的时间趋势和年龄-时期-队列效应，1935-89 年。

• DOI: 10.1007/bf00051361
• 发表时间: 1992
• 期刊: Cancer causes & control : CCC
• 作者: Zheng,T;Mayne,ST;Holford,TR;Boyle,P;Liu,W;Chen,Y;Mador,M;Flannery,J
• 通讯作者: Flannery,J