MRtrix: enabling advanced tractography and microstructure analysis of diffusion MRI in the brain

MRtrix：实现大脑中扩散 MRI 的高级纤维束成像和微观结构分析

• 批准号: EP/W030411/1
• 负责人: Jacques-Donald Tournier
• 金额: $ 58.07万
• 依托单位: King's College London
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2023
• 资助国家: 英国
• 起止时间: 2023 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=EP%2FW030411%2F1
• 关键词: MRtrix; enabling; advanced; tractography; microstructure

MRtrix is an open-source software project to provide high-quality implementations of novel and important technical innovations in the field of diffusion MRI analysis. Diffusion MRI is increasingly used to identify and study brain white matter fibre tracts and to investigate brain connectivity. MRtrix is a valuable software tool used by researchers in medical image processing and visualisation, neuroscience and neurotechnology and is already in use in at least 60 medical centres worldwide, and several commercial products. MRtrix has so far been maintained by a small team of dedicated academics. However, the success of the project and its widespread adoption now makes it impossible for the team to maintain and enhance the project to the expected standard due to time constraints. The long-term sustainability of the project will require the active participation of a wider range of developers and maintainers, and support from an active community of knowledgeable users. The aims of this project are therefore four-fold:- to implement important features that will enable use of the software in a greater range of situations, improve interoperation with other complementary software packages, and ensure MRtrix is ready for future applications.- to encourage researchers and developers to use MRtrix as the basis for the development and/or dissemination of their own methods (by improving the code documentation, providing online courses and articles, and providing rapid and responsive support); - to maintain the software, fix outstanding issues, and ease the various processes involved as much as possible.- to maximise user engagement and participation (by running workshops, providing online tutorials, and improving the documentation);This project will fund a Research Software Engineer for 3 years to achieve these objectives.

MRtrix 是一个开源软件项目，旨在提供扩散 MRI 分析领域新颖且重要的技术创新的高质量实现。扩散 MRI 越来越多地用于识别和研究大脑白质纤维束并研究大脑连接性。 MRtrix 是一款有价值的软件工具，供医学图像处理和可视化、神经科学和神经技术领域的研究人员使用，并已在全球至少 60 个医疗中心和多个商业产品中使用。迄今为止，MRtrix 由一小群专注的学者维护。然而，该项目的成功及其广泛采用现在使得团队由于时间限制而无法将项目维护和增强到预期标准。该项目的长期可持续性将需要更广泛的开发人员和维护人员的积极参与，以及知识丰富的用户社区的积极支持。因此，该项目的目标有四个方面：- 实现重要功能，使该软件能够在更广泛的情况下使用，改善与其他补充软件包的互操作性，并确保 MRtrix 为未来的应用做好准备。- 鼓励研究人员和开发人员使用 MRtrix 作为开发和/或传播自己方法的基础（通过改进代码文档、提供在线课程和文章以及提供快速响应的支持）； - 维护软件，解决突出问题，并尽可能简化所涉及的各种流程。- 最大限度地提高用户的参与度和参与度（通过举办研讨会、提供在线教程和改进文档）；该项目将资助一个研究软件工程师花了 3 年时间来实现这些目标。