CANCER RISK IN X-RAY TECHNOLOGISTS

X 射线技术人员的癌症风险

• 批准号: 3627086
• 负责人: JACK S MANDEL
• 金额: $ 15.13万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 1991
• 资助国家: 美国
• 起止时间: 1991-08-15 至 1995-08-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3627086
• 关键词: X ray; breast neoplasms; cancer risk; health surveys; human subject; leukemia; lung neoplasms; occupational hazard; questionnaires; radiation dosage; radiation related neoplasm /cancer; radiological health; thyroid neoplasm; whole body irradiation dosage; work site

The University of Minnesota has been under contract to the National Cancer Institute in evaluating the health of workers certified by the American Registry of Radiologic Technologists (ARRT) since February 1982. A 16-page optical scan questionnaire was sent to participants to obtain information on cancer history, risk factors, work history, and personal medical x-ray exposures. Over 90,000 of the 145,000 technologists under study responded to the full-length questionnaire. An additional 14,000 technologists provided information on their history of cancer, myocardial infarction, and thyroid conditions during an abbreviated telephone interview. Reported leukemias and cancers of the breast, thyroid, and lung were validated by obtaining hospital, pathology, and other reports. Computer linkage with the records of the nation's largest commercial dosimetry company has provided at least partial exposure histories on over 85,000 technologists. Additionally, specific exposure information was obtained from employers for persons who developed leukemia, or cancer of the breast, thyroid, or lung as well as for a random sample of the entire cohort. This second survey is being undertaken to obtain detailed information on cancer incidence during the years since the first questionnaire. Occupational and personal exposures to diagnostic x-rays are already coded and crude estimates of whole-body radiation doses can be made. A second follow-up will enable us to link the occurrence of subsequent cancer with these previous measures of radiation exposure. Incident cancers of the breast and thyroid are of particular interest because mortality data are incomplete.

明尼苏达大学已与国家癌症签订合同 评估美国认证的工人的健康研究所 自1982年2月以来，放射技术专家注册表（ARRT）。一页16页 光学扫描问卷已发送给参与者以获取信息 关于癌症病史，危险因素，工作历史和个人医疗X射线 暴露。 在研究中的145,000名技术人员中，有90,000多名回应 向全长问卷调查。 另外14,000名技术人员 提供有关其癌症史，心肌梗塞和 在缩写的电话采访中甲状腺条件。 报告 乳房，甲状腺和肺的白血病和癌症得到了证实 获得医院，病理和其他报告。 与计算机链接 该国最大的商业剂量法公司的记录有 至少在85,000多名技术人员上提供了至少部分暴露历史。 此外，还从雇主那里获得了特定的暴露信息 患有白血病或乳腺癌，甲状腺或肺癌的人 以及整个队列的随机样本。 正在进行第二项调查以获取有关的详细信息 自第一份问卷以来的几年中的癌症发病率。 诊断X射线的职业和个人暴露已经被编码 可以进行全身辐射剂量的粗制估计。 第二 随访将使我们能够将随后的癌症的发生与 这些先前的辐射暴露量度。 事件的癌症 乳房和甲状腺特别感兴趣，因为死亡率数据是 不完整。