LASER-INDUCED PHOTOEMISSIVE IDENTIFICATION OF CALCULI

结石的激光诱导光透射识别

• 批准号: 3495839
• 负责人: STEVEN J DAVIS
• 金额: $ 4.99万
• 依托单位: PHYSICAL SCIENCES, INC
• 依托单位国家: 美国
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-05-01 至 1989-10-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3495839
• 关键词: chemical structure; diagnosis design /evaluation; electronic spectra; emission spectrometry; fiber optics; fluorescence; laser spectrometry; lasers; photochemistry; photomultiplier; urinary calculi; urinary tract disorder diagnosis

A novel optically based diagnostic for urinary stone identification is described. The concept is based upon the well founded and sensitive technique of laser induced fluorescence (LIF). The Phase I project will determine in vitro, using several commonly found stones, whether LIF can be used to identify the composition of the stone. The photoemission spectrum observed will be recorded for several types of stones. Characteristic spectral signatures will be sought for each type. If the stones indeed shown characteristic features then one can identify unknown samples by these spectral signatures. This could lead to a new clinical device for stone classification, and, perhaps more more importantly, a minimally invasive, fiberoptic based device for in-situ identification prior to treatment.

一种新型的基于光学的尿路结石诊断方法 被描述。 这个概念是基于有充分依据和 激光诱导荧光（LIF）敏感技术。 阶段 我的项目将在体外确定，使用几种常见的 结石，是否可以用LIF来鉴定结石的成分 石头。 观察到的光发射光谱将被记录 几种类型的石头。 特征光谱特征将 为每种类型寻找。 如果宝石确实表现出特征 然后人们可以通过这些光谱来识别未知样品 签名。 这可能会带来一种新的治疗结石的临床设备 分类，也许更重要的是，最低限度的 基于侵入式光纤的设备，用于事先进行原位识别 来治疗。