FOURTH INTERNATIONAL SYMPOSIUM ON BIOLOGICAL REACTIVE

第四届生物反应国际研讨会

• 批准号: 3434801
• 负责人: ROBERT SNYDER
• 金额: $ 1万
• 依托单位: RUTGERS, THE STATE UNIV OF N.J.
• 依托单位国家: 美国
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-07-01 至 1990-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3434801
• 关键词: adduct; alkylating agents; alkylation; cell cell interaction; chemical reaction; covalent bond; travel

The object of this proposal is to solicit funds to help support an international conference entitled THE FOURTH INTERNATIONAL SYMPOSIUM ON BIOLOGICAL REACTIVE INTERMEDIATES: MOLECULAR AND CELLULAR EFFECTS. The dates of the proposed meeting is January 14- 19, 1990, and the site will be Tucson, Arizona. The funds will be used to support travel and maintenance of both foreign and American speakers and chairpeople to Tucson where they will partake in presentations and discussions on the current state of our understanding of reactive intermediates, the chemistry of reactive species and covalent binding, DNA adduct formation and repair, immunotoxicology, oxygen, mycotoxins, pyrollizidine alkaloids, nitrosamines, hepatic and non-hepatic toxicity, and human disease related to reactive metabolites. Emphasis will be placed on the role of molecular targets (protein and DNA), and on the importance of cell-cell interactions in the development of tissue lesions. The program will include a series of invited speakers and several sessions at which volunteer presentations can be made in the form of poster sessions.

该提议的目的是索取资金，以帮助支持 国际会议标题为第四国际 生物反应性中间体研讨会：分子和 细胞效应。 拟议会议的日期是1月14日 - 19，1990，该地点将是亚利桑那州图森。 资金将是 用于支持外国和美国的旅行和维护 发言人和椅子派对图森将参加 关于我们当前状态的演讲和讨论 理解反应性中间体，反应性化学 物种和共价结合，DNA加合物的形成和修复， 免疫毒理学，氧气，霉菌毒素，毒素生物碱生物碱， 亚硝胺，肝和非肝毒性以及人类疾病 与反应性代谢产物有关。 重点将放在 分子靶标（蛋白质和DNA）的作用以及重要性 在组织病变发展中的细胞 - 细胞相互作用。 该计划将包括一系列受邀演讲者和几个 可以以形式进行志愿者演讲的会议 海报会议。