MECHANISMS & CONSEQUENCES OF DEVELOPMENTAL NEUROTOXICITY

机制

• 批准号: 2885761
• 负责人: Joan Marie Cranmer
• 金额: $ 1.4万
• 依托单位: UNIV OF ARKANSAS FOR MED SCIS
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-07-01 至 2000-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2885761
• 关键词: developmental neurobiology; information dissemination; meeting /conference /symposium; metals; neurotoxicology; pesticide biological effect; solvents

SPECIFIC AIMS: Specific Aim 1: The purpose of the 17th International Neurotoxicology Conference (NTX XVII) entitled: CHILDREN'S HEALTH AND THE ENVIRONMENT: MECHANISMS AND CONSEQUENCES OF DEVELOPMENTAL NEUROTOXICOLOGY is to convene international experts as well as established and promising new researchers anywhere in the world to present, discuss and evaluate the most recent research and information concerning the mechanisms and possible consequences of developmental neurotoxicity from exposure to different classes of chemicals (metals, pesticides, endocrine disrupters, solvents) during development (i.e. as an embryo, fetus, neonate, infant, child and/or adolescent). Specific Aim 2: To organize the conference participants, tutorials, presentations, discussions, demonstrations and interactions to document major new research advances, facilitate identification of specific research gaps and potential experimental designs to answer questions. Specific Aim 3: To facilitate collaboration of scientists and help foster or initiate new multi-disciplinary research approaches to advance the science related to the theme. Specific Aim 4: To include representation from academia, government, industry, foundations and private organizations on the program as organizers, session chairs, invited speakers, poster presenters or participants. Specific Aim 5: To rapidly peer-review and disseminate findings to the scientific community. Invited speakers and other presenters in the Poster Session will submit original research papers of new data presented as well as summaries of recent findings related to the specific topics. Papers will be peer-reviewed and rapidly published in Neurotoxicology as international scientific journal that is widely disseminated, indexed and abstracted. SIGNIFICANCE: This conference will bring together a balanced representation of experts from academia, industry, governmental and non- governmental organizations to discuss what is known, identify information gaps, and help define future directions for research to advance our fundamental knowledge of the mechanisms and effects (including subtle, delayed, and long-term) from exposure to toxic chemicals during development. This conference of international experts, active researchers, regulatory scientists and other related individuals will provide information to draw upon and apply to important, scientific, environmental, clinical, epidemiological, regulatory, risk assessment, future funding issues.

具体目标： 具体目标 1：第 17 届国际神经毒理学会议 (NTX XVII) 的目的是：儿童健康与环境：发育神经毒理学的机制和后果，旨在召集国际专家以及世界各地已建立的和有前途的新研究人员介绍、讨论和评估有关发育机制和可能后果的最新研究和信息在发育过程中（即胚胎、胎儿、新生儿、婴儿、儿童和/或青少年）接触不同类别的化学物质（金属、农药、内分泌干扰物、溶剂）而产生的神经毒性。具体目标 2：组织会议参与者、教程、演示、讨论、演示和互动，以记录主要的新研究进展，促进确定具体的研究差距和潜在的实验设计以回答问题。具体目标 3：促进科学家的合作，帮助培育或启动新的多学科研究方法，以推进与主题相关的科学。具体目标 4：让学术界、政府、行业、基金会和私人组织的代表作为组织者、会议主席、受邀演讲者、海报展示者或参与者参与该计划。具体目标 5：快速进行同行评审并向科学界传播研究结果。海报会议中受邀的演讲者和其他演讲者将提交所呈现的新数据的原始研究论文以及与特定主题相关的最新发现的摘要。论文将经过同行评审并快速发表在《神经毒理学》这一国际科学期刊上，该期刊被广泛传播、索引和摘要。意义：本次会议将汇集来自学术界、工业界、政府和非政府组织的均衡代表的专家，讨论已知的信息，找出信息差距，并帮助确定未来的研究方向，以增进我们对机制和影响的基础了解（包括微妙的、延迟的和长期的）在开发过程中接触有毒化学物质。这次由国际专家、活跃研究人员、监管科学家和其他相关人士组成的会议将提供可借鉴和应用于重要的科学、环境、临床、流行病学、监管、风险评估和未来资助问题的信息。