VISUAL FUNCTIONS OF THE MONKEY PULVINAR

猴子 PULVIAR 的视觉功能

• 批准号: 3256616
• 负责人: DAVID B BENDER
• 金额: $ 8.26万
• 依托单位: STATE UNIVERSITY OF NEW YORK AT BUFFALO
• 依托单位国家: 美国
• 财政年份: 1978
• 资助国家: 美国
• 起止时间: 1978-12-01 至 1986-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3256616
• 关键词: brain mapping; electrophysiology; experimental brain lesion; eye movements; neuroanatomy; neurophysiology; single cell analysis; stereotaxic techniques; superior colliculus; visual feedback

The pulvinar is a major nucleus in the primate thalamus. It has extensive connections with the visual cortical areas and with the superior colliculus. Electrophysiological and behavioral studies in monkeys, and the effects of stroke in man, indicate that the pulvinar plays an important role in visual information processing and visuomotor integration. Our long-term goal is to understand the pulvinar's role in vision. Goals of the proposed project are to determine the contributions of striate cortex and the superior colliculus to visual information coding in the inferior pulvinar. The visual responses of pulvinar cells will be examined with microelectrode recordings in the anesthetized monkey following ablation of striate cortex or the superior colliculus. The effects of saccadic eye movements on the visual excitability of pulvinar neurons will be examined in the awake, behaving monkey. The effects of the behavioral significance of stimuli on pulvinar neuron responses will also be examined. The effects of pulvinar ablation on visually-guided eye movements will also be determined.

Pulvinar是灵长类动物丘脑的主要核。 它有广泛的 与视觉皮质区域以及上级连接 丘。 猴子的电生理学和行为研究，以及 中风在人中的影响，表明pulvinar发挥着重要的作用 在视觉信息处理和视觉运动集成中的作用。 我们的 长期目标是了解普尔维纳尔在视力中的作用。 目标 拟议的项目旨在确定条纹皮质的贡献 以及上下的高级信息编码 pulvinar。 pulvinar细胞的视觉反应将检查 消融后麻醉猴子中的微电极记录 条纹皮层或上丘。 saccadic眼的影响 将检查Pulvinar神经元视觉兴奋性的运动 在醒着，表现猴子。 行为意义的影响 还将检查刺激性神经元反应的刺激。 效果 视觉引导的眼睛运动上的脉冲消融也将是 决定。