VISUAL FUNCTIONS OF THE PULVINAR

枕骨的视觉功能

• 批准号: 3256618
• 负责人: DAVID B BENDER
• 金额: $ 13.58万
• 依托单位: STATE UNIVERSITY OF NEW YORK AT BUFFALO
• 依托单位国家: 美国
• 财政年份: 1978
• 资助国家: 美国
• 起止时间: 1978-12-01 至 1989-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3256618
• 关键词: Macaca; attention; brain mapping; electrophysiology; experimental brain lesion; eye movements; neural information processing; neuroanatomy; neurophysiology; oculomotor nuclei; single cell analysis; stereotaxic techniques; stimulus /response; superior colliculus; thalamus; visual cortex; visual feedback; visual pathways; visual stimulus

In primates, the pulvinar is the largest nucleus in the thalamus. It is closely interconnected with many areas of visual cortex, the temporal lobe and the pariental lobe, as well as with the superior colliculus. The pulvinar may play a crucial role in recovery of vision following blindness of central origin, and it has been implicated in the effects of stroke in man. It is thought to play an important role in the central processing of visual information and in the integration of eye movements with visual perception. The nature of that role is not understood. This research is part of a long-term project to understand how the pulvinar contributes to vision. The proposed research is expected to clarify the functional significance of the tectopulvinar pathway, and to clarify the different functional relationships between striate and extrastriate cortex and two pulvinar subdivisions, the inferior and lateral nuclei. One aim is to find out how eye movements affect the visual responsifeness of single neurons in the pulvinar. Microelectrode recordings will be made from the pulvinar in macaques trained to make eye movements of specified size and direction. Since any effects of eye movements are likely to be mediated by input to the pulvinar from the superior colliculus, these effects will also be measured after colliculus ablation. A second aim is to investigate the degree to which the state of directed attention and the behavioral training techniques, affect the visual responsiveness of inferior and lateral pulvinar neurons.

在灵长类动物中，pulvinar是丘脑中最大的核。 它 与许多视觉皮层紧密互连， 颞叶和偏叶，以及上司 丘。 pulvinar在恢复中可能起着至关重要的作用 视力遵循核心起源的失明，它一直 与中风的影响有关。 人们认为玩 在视觉信息的中央处理中的重要作用 以及在视觉感知的整合中。 该角色的性质尚不理解。 这项研究是 一个长期的项目，以了解pulvinar如何贡献 想象。 拟议的研究有望澄清 Tectopupulvinar途径的功能意义，并 阐明条纹和条纹之间的不同功能关系 外层皮质和两个pulvinar细分，下等 侧核。 一个目的是找出眼睛运动如何影响视觉 单个神经元在脉冲中的疑问。 微电极 录音将是由猕猴的Pulvinar制作的 使眼睛运动的大小和方向。 自此 眼动的影响可能通过输入到 来自上丘的pulvinar，这些影响也将是 在山胶消融后测量。 第二个目的是调查 关注状态的程度和 行为训练技术，影响 下脉冲神经元下侧和外侧。