DIABETES MELLITUS AND MALE SEXUAL BEHAVIOR

糖尿病与男性性行为

基本信息

批准号：
3238807
负责人：
RAUL C SCHIAVI
金额：
$ 22.35万
依托单位：
MOUNT SINAI SCHOOL OF MEDICINE OF CUNY
依托单位国家：
美国
项目类别：
财政年份：
1987
资助国家：
美国
起止时间：
1987-08-01 至 1991-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/3238807
关键词：
diabetes mellitus human middle age (35-64) human subject impotence interview male penis disorder plethysmography psychological tests psychophysiology questionnaires reflex reproductive system circulation sex behavior ultrasound blood flow measurement young adult human (21-34)

项目摘要

Remarkably little is known about the psychobiological determinants of sexual disorders in male diabetic patients. The purpose of this proposals is to assess within a cross-sectional framework the role of organic, psychological and relationship factors and their interaction in the sexual functioning of a well- defined population of male diabetics. Specifically, the central aims of the research are: 1) to provide a comprehensive description of the sexual functioning of a sample of male diabetics living in stable sexual relationships; 2) to evaluate the degree and nature of organic impairment in erectile capacity by means of nocturnal penile tumescence (NPT), bulbocavernosus (BC) reflex response latency and penile vascular assessment methods; 3) to assess systematically psychological and marital factors in relation to the sexual functioning of male diabetics; and, 4) to explore the interaction between the psychological/relationship dimensions and the physiological measures of erectile capacity in the development of erectile impotence. A sample of 120 diabetic men in adequate metabolic control, free from coexisting illnesses or medications which are likely to impair sexual function and between the ages of 21 to 65 will be selected for study. They will be compared to 60 healthy non-diabetic controls who are free from sexual dysfunctions and who meet similar inclusion/exclusion criteria. During the initial phase of the protocol, several sessions will be devoted to screening each man, acquiring informed consent, interviewing the subject and his partner to assess psychosexual behavior, evaluating psychopathology, conducting a medical evaluation and administering a battery of psychological instruments. In the second phase, the subjects will be scheduled for three EEG and NPT recording nights and for assessments of penile vascular function and bulbocavernosus reflex response latency. The relation between sexual functioning, biomedical and psychological variables will be explored by analysis of variance, analysis of covariance, correlation analysis and multiple regression techniques. Knowledge of the relative role of organic and psychological factors in the pathogenesis of diabetic sexual disorders is of critical importance for planning predictive studies and for developing effective evaluation and treatment procedures for diabetic patients. The study will provide a useful model for the assessment of sexual functioning in other organic conditions.

关于心理生物学知之甚少男性糖尿病患者性疾病的决定因素。这该建议的目的是评估横截面框架有机，心理和关系的作用因素及其在井的性功能中的相互作用定义的男性糖尿病患者。具体来说，中央研究的目的是：1）提供全面的雄性样本的性功能的描述生活在稳定的性关系中的糖尿病患者； 2）评估勃起能力的有机损害的程度和性质夜间阴茎肿瘤（NPT），Bulbocavernosus的手段（BC）反射反应潜伏期和阴茎血管评估方法; 3）评估系统心理和婚姻与男性糖尿病患者的性功能有关的因素；和，4）探索心理/关系维度和生理勃起的勃起能力的度量阳ot。有120名糖尿病男性的样本中有足够的代谢控制，没有共存的疾病或药物可能会损害性功能以及21至65岁的年龄之间将被选为研究。他们将与60个健康没有性功能障碍的非糖尿病控制符合类似的包含/排除标准的人。在协议的初始阶段，将有几个会话致力于筛选每个人，获得知情同意，采访主题及其伴侣评估心理婚姻行为，评估心理病理学，进行医学评估和管理一系列心理乐器。在第二阶段，受试者将被安排对于三个脑电图和NPT录制的夜晚以及评估阴茎血管功能和囊泡反射响应潜伏期。性功能，生物医学和心理变量将通过差异分析来探讨协方差分析，相关分析和多个回归技术。了解有机的相对作用和糖尿病性发病机理的心理因素疾病对于计划预测研究至关重要并用于制定有效的评估和治疗程序适用于糖尿病患者。该研究将为在其他有机条件下对性功能的评估。