14 ERA-CAPS An Effector- and Genomics-Assisted Pipeline for Necrotrophic Pathogen Resistance Breeding in Wheat

14 ERA-CAPS 小麦坏死营养型病原体抗性育种的效应器和基因组学辅助管道

• 批准号: BB/N00518X/1
• 负责人: James Cockram
• 金额: $ 81.91万
• 依托单位: National Institute of Agricultural Botany
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2015
• 资助国家: 英国
• 起止时间: 2015 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=BB%2FN00518X%2F1
• 关键词: 14; ERA; CAPS; Effector; Genomics

EfectaWheat is a partnership of six complementary institutes from the UK (NIAB, FERA), Germany (LFL), Denmark (AARHUS), Norway (NMBU) and Australia (CCDM). The partners form a multidisciplinary team focusing on the economically important wheat leaf spot group (LSG) of necrotrophic pathogens: Parastagonospora nodorum (Pn, cause of Septoria nodorum blotch; SNB), Zymoseptoria tritici (Zt, Septoria tritici blotch; STB) and Pyrenophora tritici-repentis (Ptr, tan spot; TS).Recently available resources in wheat, including high-resolution genetic mapping populations and high-density genotyping, will be combined with emerging tools and approaches in the pathogens, such as pathogen genome resequencing, and identification of pathogen-produced molecules that mediate infection (termed, 'effectors). These approaches will complement the project partners' expertise in pathogen diagnostics, virulence assessment and field pathotesting across all partner countries. These combine to deliver a genomics- and effector-based pipeline for the genetic dissection of LSG host-pathogen interactions in Europe. The unique positions of partners at the interface between crop research and translation ensure effective dissemination of project outputs to European agri-industry. This approach has been successfully implemented by CCDM for SNB and TS in Australia. This project will extend the approach to Europe. All resources generated will be made available to the research and industrial communities to facilitate practical exploitation.

EfectaWheat 是英国 (NIAB、FERA)、德国 (LFL)、丹麦 (AARHUS)、挪威 (NMBU) 和澳大利亚 (CCDM) 六家互补机构的合作伙伴。合作伙伴组成了一个多学科团队，专注于经济上重要的坏死营养病原体小麦叶斑病群 (LSG)：Parastagonospora nodorum（Pn，小麦壳针孢斑病的病因；SNB）、小麦发酵壳孢（Zt，小麦壳针孢斑病；STB）和小麦核腔菌（Pyrenophora tritici） -repentis（Ptr，棕褐色斑点；TS）。小麦的最新可用资源，包括高分辨率遗传图谱人群和高密度基因分型，将与病原体的新兴工具和方法相结合，例如病原体基因组重新测序，以及鉴定病原体产生的介导感染的分子（称为“效应物”）。这些方法将补充项目合作伙伴在所有合作伙伴国家的病原体诊断、毒力评估和现场病理测试方面的专业知识。这些结合起来，为欧洲 LSG 宿主-病原体相互作用的基因解析提供了基于基因组学和效应子的管道。合作伙伴在作物研究和转化之间的独特地位确保了项目成果向欧洲农业工业的有效传播。 CCDM 已在澳大利亚为 SNB 和 TS 成功实施了该方法。该项目将把这种方法推广到欧洲。产生的所有资源将提供给研究界和工业界，以促进实际开发。

项目成果

Wheat genetic loci conferring resistance to stripe rust in the face of genetically diverse races of the fungus Puccinia striiformis f. sp. tritici.

小麦遗传位点在面对遗传多样化的真菌条锈菌 f 时赋予对条锈病的抗性。

• DOI: http://dx.10.1007/s00122-021-03967-z
• 发表时间: 2022
• 期刊: TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik
• 作者: Bouvet L

Genetic analysis of wheat sensitivity to the ToxB fungal effector from Pyrenophora tritici-repentis, the causal agent of tan spot.

小麦对白斑病致病菌 ToxB 真菌效应子敏感性的遗传分析。

• DOI: http://dx.10.17863/cam.62950
• 发表时间: 2020
• 作者: Corsi B

Wheat genetic loci conferring resistance to stripe rust in the face of genetically diverse races of the fungus Puccinia striiformis f. sp. tritici.

小麦遗传位点在面对遗传多样化的真菌条锈菌 f 时赋予对条锈病的抗性。

• DOI: http://dx.10.17863/cam.80008
• 发表时间: 2022
• 作者: Bouvet L

The Evolving Battle Between Yellow Rust and Wheat: Implications for Global Food Security

黄锈病与小麦之间不断演变的斗争：对全球粮食安全的影响

• DOI: http://dx.10.21203/rs.3.rs-557233/v1
• 发表时间: 2021
• 作者: Bouvet L

A roadmap for gene functional characterisation in wheat

小麦基因功能表征路线图

• DOI: http://dx.10.7287/peerj.preprints.26877v2
• 发表时间: 2019
• 作者: Adamski N