DESIGN STUDY FOR THE UCSF PROTON FACILITY

加州大学旧金山分校质子设施的设计研究

• 批准号: 3201351
• 负责人: JOSE ALONSO
• 金额: $ 228.06万
• 依托单位: UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB
• 依托单位国家: 美国
• 财政年份: 1991
• 资助国家: 美国
• 起止时间: 1991-09-30 至 1994-03-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3201351
• 关键词: biomedical equipment development; biomedical equipment safety; biomedical facility; building /facility design /renovation; clinical biomedical equipment; particle accelerators; proton beam; radiation dosage; radiation therapy; safety equipment

The University of California at San Francisco (UCSF) is planning to build a proton therapy facility as a part of its new Comprehensive Cancer Center. The UCSF Proton Facility will be installed in the lower levels of a new building housing research facilities for the Cancer Center, to be located at UCSF's Mount Zion Hospital and Medical Center site. UCSF and LBL are entering into an agreement to advance this project; LBL will design the accelerator, beam transport and beam delivery systems, will oversee their construction and will be responsible for commissioning and initial operation of the Proton Facility at Mount Zion. As construction of the accelerator systems will probably be finished at least one year prior to the new building's completion, the accelerator will be installed within the experimental area of the Bevalac, and connected to the currently-operating treatment facilities. This will allow for full commissioning of the accelerator, from initial operation to full readiness for clinical use of the proton beam, prior to its transport to its permanent location at Mount Zion. Work to be performed this coming year as part of this Grant application is critical to the success of this project. Very early in the year decisions will be made on the major specifications and architecture of the technical systems. The remainder of the time will be spent in full-scale design and costing activities, leading to the production of a Full Design Report. Detailed designs will emerge from very close interfacing between clinical, medical physics, accelerator physics and engineering personnel; final specifications for each element emerging during the course of the year as a result of design, function and cost optimization studies. The design report will include scope and costing of conventional aspects of the project as well; we will be working with A&E representatives of UCSF to integrate the UCSF Proton Facility into the Comprehensive Cancer Center plans. An analysis of regulatory requirements, and costs for compliance documents will be estimated as well. Finally, a model for operations of the facility will be developed, to identify required ongoing operations costs. The Full Design Report will be a blueprint for the entire UCSF Proton Facility, it will be a document essentially suitable as a bid package.

加州大学旧金山大学（UCSF）计划建造 质子疗法设施是其新综合癌症的一部分 中心。 UCSF质子设施将安装在较低级别 癌症中心的新建筑物住房研究设施 位于UCSF的锡安山医院和医疗中心地点。 UCSF LBL正在签订协议以推进该项目； LBL会 设计加速器，光束传输和光束输送系统，将 监督其建设，并将负责调试和 质子设施在锡安山上的初始操作。 作为建筑 加速器系统的中至少将完成至少一年 在新大楼完成之前，将安装加速器 在Bevalac的实验区域内，并连接到 当前运营的治疗设施。 这将允许完整 从初始操作到全面的加速器的调试 准备质子梁的临床使用，然后将其运输到 它在锡安山的永久位置。 工作要来的工作 作为本赠款申请的一部分，这一年对于成功的成功至关重要 项目。 一年中很早就将对专业做出决定 技术系统的规格和体系结构。 其余的 这段时间将花在全面设计和成本上的活动中， 导致制作完整的设计报告。 详细的设计将 从临床，医学物理学之间的非常紧密的接口中出现 加速器物理和工程人员；最终规格 由于 设计，功能和成本优化研究。 设计报告将 还包括项目的范围和成本量； 我们将与UCSF的A＆E代表合作以整合UCSF 质子设施进入综合癌症中心计划。 分析 监管要求和合规文件的成本将是 也估计。 最后，设施运营的模型将 开发，以确定所需的持续运营成本。 完整 设计报告将是整个UCSF质子设施的蓝图， 它将是一份本质上适合出价包的文档。